Antibody data

Product number
BS8238
Provider
Bioworld Technology, Inc
Product name
ERAF polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS8238
Antibody type
Polyclonal
Antigen
Recombinant full length Human ERAF.
Description
Ï«-hemoglobin stabilizing protein (AHSP), also designated erythroid associated factor (ERAF), is an erythroid-specific protein that acts as a chaperone to prevent the aggregation of Ï«-hemoglobin during normal erythroid cell development.It specifically protects free Ï«-hemoglobin from precipitation in live cells and in solution. It forms a heterodimer with free Ï«-hemoglobin, but not with ÉÇ-hemoglobin or hemoglobin A (Ï«2-ÉÇ-2). AHSP localizes to the cytoplasm and is expressed in the blood and bone marrow. The AHSP protein is downregulated in transmissible spongiform encephalopathies (TSEs). AHSP may regulate pathological states of Ï«-hemoglobin excess such as ÉÇ-thalassemia,a group of hereditary disorders involving the decreased production of normal adult hemoglobin (HbA) that are characterized by a deficiency in the synthesis of ÉÇ-globin chains.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -