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Learn600-401-B62S
antibody from Rockland Immunochemicals, Inc.
Targeting: CASZ1
castor, cst, FLJ20321, SRG, ZNF693
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 600-401-B62S - Provider product page
- Provider
- Rockland Immunochemicals, Inc.
- Proper citation
- Rockland Cat#600-401-B62S, RRID:AB_1961496
- Product name
- Anti-CASZ1 (RABBIT) Antibody - 600-401-B62S
- Antibody type
- Polyclonal
- Vial size
- 25 µl
Submitted references CASZ1 induces skeletal muscle and rhabdomyosarcoma differentiation through a feed-forward loop with MYOD and MYOG.
Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups.
Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma.
SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors.
CASZ1b, the short isoform of CASZ1 gene, coexpresses with CASZ1a during neurogenesis and suppresses neuroblastoma cell growth.
Liu Z, Zhang X, Lei H, Lam N, Carter S, Yockey O, Xu M, Mendoza A, Hernandez ER, Wei JS, Khan J, Yohe ME, Shern JF, Thiele CJ
Nature communications 2020 Feb 14;11(1):911
Nature communications 2020 Feb 14;11(1):911
Molecular Profiling Defines Evolutionarily Conserved Transcription Factor Signatures of Major Vestibulospinal Neuron Groups.
Lunde A, Okaty BW, Dymecki SM, Glover JC
eNeuro 2019 Jan-Feb;6(1)
eNeuro 2019 Jan-Feb;6(1)
Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma.
Liu Z, Lam N, Wang E, Virden RA, Pawel B, Attiyeh EF, Maris JM, Thiele CJ
Oncogene 2017 Jan 5;36(1):97-109
Oncogene 2017 Jan 5;36(1):97-109
SFMBT1 functions with LSD1 to regulate expression of canonical histone genes and chromatin-related factors.
Zhang J, Bonasio R, Strino F, Kluger Y, Holloway JK, Modzelewski AJ, Cohen PE, Reinberg D
Genes & development 2013 Apr 1;27(7):749-66
Genes & development 2013 Apr 1;27(7):749-66
CASZ1b, the short isoform of CASZ1 gene, coexpresses with CASZ1a during neurogenesis and suppresses neuroblastoma cell growth.
Liu Z, Naranjo A, Thiele CJ
PloS one 2011 Apr 7;6(4):e18557
PloS one 2011 Apr 7;6(4):e18557
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Supportive validation
- Submitted by
- Rockland Immunochemicals, Inc. (provider)
- Main image
- Experimental details
- Western blot using Rockland's anti-hCASZ1 antibody. This blot shows detection of endogenous and transfected human CASZ1 protein in fresh whole cell lysate (~30 µg). Protein was resolved by SDS-PAGE and transferred onto nitrocellulose. After blocking, the membrane was probed with the primary antibody diluted to 1:1,000, incubated 1.5 hours at room temperature, and incubated with HRP-conjugated Goat Anti-Rabbit antibody for 45 min. at room temperature. Lane 1, BE2(s) cell lysate. Lane 2, BE2(N) cell lysate. Lane 3, SY5Y transfected with hCas5 (125kDa). Lane 4, SY5Y transfected with hCas11 (190kDa). Personal communication, Carol Thiele, NCI, Bethesda, MD
- Validation comment
- Western Blot
