NBP1-86908

antibody from Novus Biologicals

Targeting: TCOF1 TCS, treacle

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

NBP1-86908

Provider

Novus Biologicals

Proper citation

Novus Cat#NBP1-86908, RRID:AB_11017925

Product name

Rabbit Polyclonal Treacher Collins syndrome protein Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Specificity of human Treacher Collins syndrome protein antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

0.1 ml

Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

References

Submitted references

The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage.

Larsen DH, Hari F, Clapperton JA, Gwerder M, Gutsche K, Altmeyer M, Jungmichel S, Toledo LI, Fink D, Rask MB, Grøfte M, Lukas C, Nielsen ML, Smerdon SJ, Lukas J, Stucki M
Nature cell biology 2014 Aug;16(8):792-803

Western blot

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Western Blot: Treacher Collins syndrome protein Antibody [NBP1-86908] - Analysis in human cell line CACO-2.

Immunohistochemistry

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human rectum shows moderate nucleolar and cytoplasmic positivity in glandular cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human skin.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human cerebral cortex, kidney, lymph node and skin using Anti-TCOF1 antibody NBP1-86908 (A) shows similar protein distribution across tissues to independent antibody NBP1-86909 (B).

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human lymph node.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human cerebral cortex.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human kidney.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human liver shows very low positivity in hepatocytes.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human Fallopian tube shows moderate nuclear positivity in glandular cells.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human testis shows weak to moderate nuclear and nucleolar positivity in cells in seminiferous ducts.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Immunohistochemistry-Paraffin: Treacher Collins syndrome protein Antibody [NBP1-86908] - Staining of human rectum shows moderate nuclear and nucleolar positivity in glandular cells.