ABIN968082

antibody from antibodies-online

Targeting: SHC3 N-Shc, NSHC, SHCC

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN968082

Provider

antibodies-online

Product name

anti-SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3) (AA 239-374) antibody

Antibody type

Monoclonal

Antigen

Mouse ShcC aa. 239-374

Description

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Human, Mouse, Rat

Host

Mouse

Epitope

AA 239-374

Isotype

IgG

Antibody clone number

23-ShcC

Vial size

50 μg

Storage

Store undiluted at -20° C.

References

Submitted references

Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.

Tarr PE, Roncarati R, Pelicci G, Pelicci PG, D'Adamio L
The Journal of biological chemistry 2002 May 10;277(19):16798-804

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Shc signaling in differentiating neural progenitor cells.

Conti L, Sipione S, Magrassi L, Bonfanti L, Rigamonti D, Pettirossi V, Peschanski M, Haddad B, Pelicci P, Milanesi G, Pelicci G, Cattaneo E
Nature neuroscience 2001 Jun;4(6):579-86

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A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.

O'Bryan JP, Songyang Z, Cantley L, Der CJ, Pawson T
Proceedings of the National Academy of Sciences of the United States of America 1996 Apr 2;93(7):2729-34