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- Antibody Data
- Antigen structure
- References [20]
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- Immunohistochemistry [1]
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- Product number
- 22524-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- DAT antibody
- Antibody type
- Polyclonal
- Description
- DAT antibody (Cat. #22524-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Reconstituting neurovascular unit with primary neural stem cells and brain microvascular endothelial cells in three-dimensional matrix.
Exposure to Melamine cyanuric acid in adolescent mice caused emotional disorder and behavioral disorder.
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
The neuroprotective effects of isoquercitrin purified from apple pomace by high-speed countercurrent chromatography in the MPTP acute mouse model of Parkinson's disease.
Iron deficiency in pregnancy: Influence on sleep, behavior, and molecular markers of adult male offspring.
Gait Deficits and Loss of Striatal Tyrosine Hydroxlase/Trk-B are Restored Following 7,8-Dihydroxyflavone Treatment in a Progressive MPTP Mouse Model of Parkinson's Disease.
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids.
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Differentiation of adult human retinal pigment epithelial cells into dopaminergic-like cells in vitro and in the recipient monkey brain.
Effects of sleep disruption on stress, nigrostriatal markers, and behavior in a chronic/progressive MPTP male mouse model of parkinsonism.
Andrographolide alleviates Parkinsonism in MPTP-PD mice via targeting mitochondrial fission mediated by dynamin-related protein 1.
The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling.
Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease.
Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway.
Exercise in an animal model of Parkinson's disease: Motor recovery but not restoration of the nigrostriatal pathway.
Echinacoside's nigrostriatal dopaminergic protection against 6-OHDA-Induced endoplasmic reticulum stress through reducing the accumulation of Seipin.
Exercise intervention increases spontaneous locomotion but fails to attenuate dopaminergic system loss in a progressive MPTP model in aged mice.
Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease.
Protective effects of cholecystokinin-8 on methamphetamine-induced behavioral changes and dopaminergic neurodegeneration in mice.
Wang H, Yang H, Shi Y, Xiao Y, Yin Y, Jiang B, Ren H, Chen W, Xue Q, Xu X
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Brain pathology (Zurich, Switzerland) 2021 Sep;31(5):e12940
Exposure to Melamine cyanuric acid in adolescent mice caused emotional disorder and behavioral disorder.
Wang S, Zhang J, Zhang S, Shi F, Feng D, Feng X
Ecotoxicology and environmental safety 2021 Mar 15;211:111938
Ecotoxicology and environmental safety 2021 Mar 15;211:111938
Asparagine endopeptidase cleaves synaptojanin 1 and triggers synaptic dysfunction in Parkinson's disease.
Zou L, Zhang X, Xiong M, Meng L, Tian Y, Pan L, Yuan X, Chen G, Wang Z, Bu L, Yao Z, Zhang Z, Ye K, Zhang Z
Neurobiology of disease 2021 Jul;154:105326
Neurobiology of disease 2021 Jul;154:105326
The neuroprotective effects of isoquercitrin purified from apple pomace by high-speed countercurrent chromatography in the MPTP acute mouse model of Parkinson's disease.
Liu C, Wang W, Li H, Liu J, Zhang P, Cheng Y, Qin X, Hu Y, Wei Y
Food & function 2021 Jul 7;12(13):6091-6101
Food & function 2021 Jul 7;12(13):6091-6101
Iron deficiency in pregnancy: Influence on sleep, behavior, and molecular markers of adult male offspring.
Franco B, Mota DS, Daubian-Nosé P, Rodrigues NA, Simino LAP, de Fante T, Bezerra RMN, Manchado Gobatto FB, Manconi M, Torsoni AS, Esteves AM
Journal of neuroscience research 2021 Dec;99(12):3325-3338
Journal of neuroscience research 2021 Dec;99(12):3325-3338
Gait Deficits and Loss of Striatal Tyrosine Hydroxlase/Trk-B are Restored Following 7,8-Dihydroxyflavone Treatment in a Progressive MPTP Mouse Model of Parkinson's Disease.
Massaquoi MS, Liguore WA, Churchill MJ, Moore C, Melrose HL, Meshul CK
Neuroscience 2020 May 1;433:53-71
Neuroscience 2020 May 1;433:53-71
Reversing a model of Parkinson's disease with in situ converted nigral neurons.
Qian H, Kang X, Hu J, Zhang D, Liang Z, Meng F, Zhang X, Xue Y, Maimon R, Dowdy SF, Devaraj NK, Zhou Z, Mobley WC, Cleveland DW, Fu XD
Nature 2020 Jun;582(7813):550-556
Nature 2020 Jun;582(7813):550-556
PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids.
Kuge H, Miyamoto I, Yagyu KI, Honke K
Journal of lipid research 2020 Dec;61(12):1747-1763
Journal of lipid research 2020 Dec;61(12):1747-1763
Catalpol Exerts a Neuroprotective Effect in the MPTP Mouse Model of Parkinson's Disease.
Wang LY, Yu X, Li XX, Zhao YN, Wang CY, Wang ZY, He ZY
Frontiers in aging neuroscience 2019;11:316
Frontiers in aging neuroscience 2019;11:316
Differentiation of adult human retinal pigment epithelial cells into dopaminergic-like cells in vitro and in the recipient monkey brain.
Li S, Zhang H, Wang A, Liu Y, Liu H, Yue F, Abulaiti X, Zhang C, Li L
Molecular medicine (Cambridge, Mass.) 2019 Mar 29;25(1):9
Molecular medicine (Cambridge, Mass.) 2019 Mar 29;25(1):9
Effects of sleep disruption on stress, nigrostriatal markers, and behavior in a chronic/progressive MPTP male mouse model of parkinsonism.
Xu M, Bohlen JK, Moore C, Nipper MA, Finn DA, Jones CE, Lim MM, Meshul CK
Journal of neuroscience research 2019 Dec;97(12):1706-1719
Journal of neuroscience research 2019 Dec;97(12):1706-1719
Andrographolide alleviates Parkinsonism in MPTP-PD mice via targeting mitochondrial fission mediated by dynamin-related protein 1.
Geng J, Liu W, Gao J, Jiang C, Fan T, Sun Y, Qin ZH, Xu Q, Guo W, Gao J
British journal of pharmacology 2019 Dec;176(23):4574-4591
British journal of pharmacology 2019 Dec;176(23):4574-4591
The loss of dopaminergic neurons in DEC1 deficient mice potentially involves the decrease of PI3K/Akt/GSK3β signaling.
Zhu Z, Yichen W, Ziheng Z, Dinghao G, Ming L, Wei L, Enfang S, Gang H, Honda H, Jian Y
Aging 2019 Dec 28;11(24):12733-12753
Aging 2019 Dec 28;11(24):12733-12753
Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease.
Churchill MJ, Cantu MA, Kasanga EA, Moore C, Salvatore MF, Meshul CK
Neuroscience 2019 Aug 21;414:8-27
Neuroscience 2019 Aug 21;414:8-27
Downregulation of DEC1 contributes to the neurotoxicity induced by MPP+ by suppressing PI3K/Akt/GSK3β pathway.
Zhu Z, Wang YW, Ge DH, Lu M, Liu W, Xiong J, Hu G, Li XP, Yang J
CNS neuroscience & therapeutics 2017 Sep;23(9):736-747
CNS neuroscience & therapeutics 2017 Sep;23(9):736-747
Exercise in an animal model of Parkinson's disease: Motor recovery but not restoration of the nigrostriatal pathway.
Churchill MJ, Pflibsen L, Sconce MD, Moore C, Kim K, Meshul CK
Neuroscience 2017 Sep 17;359:224-247
Neuroscience 2017 Sep 17;359:224-247
Echinacoside's nigrostriatal dopaminergic protection against 6-OHDA-Induced endoplasmic reticulum stress through reducing the accumulation of Seipin.
Zhang Y, Long H, Zhou F, Zhu W, Ruan J, Zhao Y, Lu Y
Journal of cellular and molecular medicine 2017 Dec;21(12):3761-3775
Journal of cellular and molecular medicine 2017 Dec;21(12):3761-3775
Exercise intervention increases spontaneous locomotion but fails to attenuate dopaminergic system loss in a progressive MPTP model in aged mice.
Hood RL, Liguore WA, Moore C, Pflibsen L, Meshul CK
Brain research 2016 Sep 1;1646:535-542
Brain research 2016 Sep 1;1646:535-542
Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease.
Sconce MD, Churchill MJ, Greene RE, Meshul CK
Neuroscience 2015 Jul 23;299:156-74
Neuroscience 2015 Jul 23;299:156-74
Protective effects of cholecystokinin-8 on methamphetamine-induced behavioral changes and dopaminergic neurodegeneration in mice.
Gou H, Wen D, Ma C, Li M, Li Y, Zhang W, Liu L, Cong B
Behavioural brain research 2015 Apr 15;283:87-96
Behavioural brain research 2015 Apr 15;283:87-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DAT antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human DAT. This antibody recognizes human, mouse, rat antigen. The DAT antibody has been validated for the following applications: ELISA, WB, IHC analysis.
