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- Antibody Data
- Antigen structure
- References [31]
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- Product number
- NBP1-41123 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-41123, RRID:AB_10005026
- Product name
- Sheep Polyclonal GAP-43 Antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse, Rat, Canine, Feline, Hamster, Simian
- Host
- Sheep
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Small-Molecule Stabilization of 14-3-3 Protein-Protein Interactions Stimulates Axon Regeneration.
Nasal neuron PET imaging quantifies neuron generation and degeneration.
PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system.
The expression pattern of EVA1C, a novel Slit receptor, is consistent with an axon guidance role in the mouse nervous system.
Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation.
Counteracting the Nogo receptor enhances optic nerve regeneration if retinal ganglion cells are in an active growth state.
Macrophage-derived factors stimulate optic nerve regeneration.
Inosine induces axonal rewiring and improves behavioral outcome after stroke.
Lens injury stimulates axon regeneration in the mature rat optic nerve.
Inosine stimulates extensive axon collateral growth in the rat corticospinal tract after injury.
Inosine stimulates extensive axon collateral growth in the rat corticospinal tract after injury.
Levels of the growth-associated protein GAP-43 are selectively increased in association cortices in schizophrenia.
Levels of the growth-associated protein GAP-43 are selectively increased in association cortices in schizophrenia.
Evidence for axonal sprouting in the anterior pituitary following adrenalectomy in the rat.
Evidence for axonal sprouting in the anterior pituitary following adrenalectomy in the rat.
Inhibition of neurite outgrowth following intracellular delivery of anti-GAP-43 antibodies depends upon culture conditions and method of neurite induction.
GAP-43 expression in primary sensory neurons following central axotomy.
Innervation of the rat anterior and neurointermediate pituitary visualized by immunocytochemistry for the growth-associated protein GAP-43.
Anatomic distribution of the growth-associated protein GAP-43 in the developing human brainstem.
Anatomic distribution of the growth-associated protein GAP-43 in the developing human brainstem.
Denervation of the motor endplate results in the rapid expression by terminal Schwann cells of the growth-associated protein GAP-43.
Vibrissectomy induced changes in GAP-43 immunoreactivity in the adult rat barrel cortex.
Phospholipid-mediated delivery of anti-GAP-43 antibodies into neuroblastoma cells prevents neuritogenesis.
Abnormal retinal projections alter GAP-43 patterns in the diencephalon.
Abnormal retinal projections alter GAP-43 patterns in the diencephalon.
Transient patterns of GAP-43 expression during the formation of barrels in the rat somatosensory cortex.
Immunoreactive GAP-43 in the neuropil of adult rat neostriatum: localization in unmyelinated fibers, axon terminals, and dendritic spines.
Peripheral nerve regeneration induces elevated expression of GAP-43 in the brainstem trigeminal complex of adult hamsters.
Peripheral nerve regeneration induces elevated expression of GAP-43 in the brainstem trigeminal complex of adult hamsters.
Immunohistochemical localization of GAP-43 in the developing hamster retinofugal pathway.
Anatomical distribution of the growth-associated protein GAP-43/B-50 in the adult rat brain.
Kaplan A, Morquette B, Kroner A, Leong S, Madwar C, Sanz R, Banerjee SL, Antel J, Bisson N, David S, Fournier AE
Neuron 2017 Mar 8;93(5):1082-1093.e5
Neuron 2017 Mar 8;93(5):1082-1093.e5
Nasal neuron PET imaging quantifies neuron generation and degeneration.
Van de Bittner GC, Riley MM, Cao L, Ehses J, Herrick SP, Ricq EL, Wey HY, O'Neill MJ, Ahmed Z, Murray TK, Smith JE, Wang C, Schroeder FA, Albers MW, Hooker JM
The Journal of clinical investigation 2017 Feb 1;127(2):681-694
The Journal of clinical investigation 2017 Feb 1;127(2):681-694
PCAF-dependent epigenetic changes promote axonal regeneration in the central nervous system.
Puttagunta R, Tedeschi A, Sória MG, Hervera A, Lindner R, Rathore KI, Gaub P, Joshi Y, Nguyen T, Schmandke A, Laskowski CJ, Boutillier AL, Bradke F, Di Giovanni S
Nature communications 2014 Apr 1;5:3527
Nature communications 2014 Apr 1;5:3527
The expression pattern of EVA1C, a novel Slit receptor, is consistent with an axon guidance role in the mouse nervous system.
James G, Foster SR, Key B, Beverdam A
PloS one 2013;8(9):e74115
PloS one 2013;8(9):e74115
Switching mature retinal ganglion cells to a robust growth state in vivo: gene expression and synergy with RhoA inactivation.
Fischer D, Petkova V, Thanos S, Benowitz LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Oct 6;24(40):8726-40
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Oct 6;24(40):8726-40
Counteracting the Nogo receptor enhances optic nerve regeneration if retinal ganglion cells are in an active growth state.
Fischer D, He Z, Benowitz LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Feb 18;24(7):1646-51
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Feb 18;24(7):1646-51
Macrophage-derived factors stimulate optic nerve regeneration.
Yin Y, Cui Q, Li Y, Irwin N, Fischer D, Harvey AR, Benowitz LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Mar 15;23(6):2284-93
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003 Mar 15;23(6):2284-93
Inosine induces axonal rewiring and improves behavioral outcome after stroke.
Chen P, Goldberg DE, Kolb B, Lanser M, Benowitz LI
Proceedings of the National Academy of Sciences of the United States of America 2002 Jun 25;99(13):9031-6
Proceedings of the National Academy of Sciences of the United States of America 2002 Jun 25;99(13):9031-6
Lens injury stimulates axon regeneration in the mature rat optic nerve.
Leon S, Yin Y, Nguyen J, Irwin N, Benowitz LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000 Jun 15;20(12):4615-26
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000 Jun 15;20(12):4615-26
Inosine stimulates extensive axon collateral growth in the rat corticospinal tract after injury.
Benowitz LI, Goldberg DE, Madsen JR, Soni D, Irwin N
Proceedings of the National Academy of Sciences of the United States of America 1999 Nov 9;96(23):13486-90
Proceedings of the National Academy of Sciences of the United States of America 1999 Nov 9;96(23):13486-90
Inosine stimulates extensive axon collateral growth in the rat corticospinal tract after injury.
Benowitz LI, Goldberg DE, Madsen JR, Soni D, Irwin N
Proceedings of the National Academy of Sciences of the United States of America 1999 Nov 9;96(23):13486-90
Proceedings of the National Academy of Sciences of the United States of America 1999 Nov 9;96(23):13486-90
Levels of the growth-associated protein GAP-43 are selectively increased in association cortices in schizophrenia.
Perrone-Bizzozero NI, Sower AC, Bird ED, Benowitz LI, Ivins KJ, Neve RL
Proceedings of the National Academy of Sciences of the United States of America 1996 Nov 26;93(24):14182-7
Proceedings of the National Academy of Sciences of the United States of America 1996 Nov 26;93(24):14182-7
Levels of the growth-associated protein GAP-43 are selectively increased in association cortices in schizophrenia.
Perrone-Bizzozero NI, Sower AC, Bird ED, Benowitz LI, Ivins KJ, Neve RL
Proceedings of the National Academy of Sciences of the United States of America 1996 Nov 26;93(24):14182-7
Proceedings of the National Academy of Sciences of the United States of America 1996 Nov 26;93(24):14182-7
Evidence for axonal sprouting in the anterior pituitary following adrenalectomy in the rat.
Lu CR, Meng FT, Benowitz LI, Ju G
The Journal of endocrinology 1995 Oct;147(1):161-6
The Journal of endocrinology 1995 Oct;147(1):161-6
Evidence for axonal sprouting in the anterior pituitary following adrenalectomy in the rat.
Lu CR, Meng FT, Benowitz LI, Ju G
The Journal of endocrinology 1995 Oct;147(1):161-6
The Journal of endocrinology 1995 Oct;147(1):161-6
Inhibition of neurite outgrowth following intracellular delivery of anti-GAP-43 antibodies depends upon culture conditions and method of neurite induction.
Shea TB, Benowitz LI
Journal of neuroscience research 1995 Jun 15;41(3):347-54
Journal of neuroscience research 1995 Jun 15;41(3):347-54
GAP-43 expression in primary sensory neurons following central axotomy.
Chong MS, Reynolds ML, Irwin N, Coggeshall RE, Emson PC, Benowitz LI, Woolf CJ
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994 Jul;14(7):4375-84
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994 Jul;14(7):4375-84
Innervation of the rat anterior and neurointermediate pituitary visualized by immunocytochemistry for the growth-associated protein GAP-43.
Paden CM, Moffett CW, Benowitz LI
Endocrinology 1994 Jan;134(1):503-6
Endocrinology 1994 Jan;134(1):503-6
Anatomic distribution of the growth-associated protein GAP-43 in the developing human brainstem.
Kinney HC, Rava LA, Benowitz LI
Journal of neuropathology and experimental neurology 1993 Jan;52(1):39-54
Journal of neuropathology and experimental neurology 1993 Jan;52(1):39-54
Anatomic distribution of the growth-associated protein GAP-43 in the developing human brainstem.
Kinney HC, Rava LA, Benowitz LI
Journal of neuropathology and experimental neurology 1993 Jan;52(1):39-54
Journal of neuropathology and experimental neurology 1993 Jan;52(1):39-54
Denervation of the motor endplate results in the rapid expression by terminal Schwann cells of the growth-associated protein GAP-43.
Woolf CJ, Reynolds ML, Chong MS, Emson P, Irwin N, Benowitz LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992 Oct;12(10):3999-4010
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992 Oct;12(10):3999-4010
Vibrissectomy induced changes in GAP-43 immunoreactivity in the adult rat barrel cortex.
Dunn-Meynell AA, Benowitz LI, Levin BE
The Journal of comparative neurology 1992 Jan 8;315(2):160-70
The Journal of comparative neurology 1992 Jan 8;315(2):160-70
Phospholipid-mediated delivery of anti-GAP-43 antibodies into neuroblastoma cells prevents neuritogenesis.
Shea TB, Perrone-Bizzozero NI, Beermann ML, Benowitz LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991 Jun;11(6):1685-90
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991 Jun;11(6):1685-90
Abnormal retinal projections alter GAP-43 patterns in the diencephalon.
Moya KL, Benowitz LI, Schneider GE
Brain research 1990 Sep 17;527(2):259-65
Brain research 1990 Sep 17;527(2):259-65
Abnormal retinal projections alter GAP-43 patterns in the diencephalon.
Moya KL, Benowitz LI, Schneider GE
Brain research 1990 Sep 17;527(2):259-65
Brain research 1990 Sep 17;527(2):259-65
Transient patterns of GAP-43 expression during the formation of barrels in the rat somatosensory cortex.
Erzurumlu RS, Jhaveri S, Benowitz LI
The Journal of comparative neurology 1990 Feb 15;292(3):443-56
The Journal of comparative neurology 1990 Feb 15;292(3):443-56
Immunoreactive GAP-43 in the neuropil of adult rat neostriatum: localization in unmyelinated fibers, axon terminals, and dendritic spines.
DiFiglia M, Roberts RC, Benowitz LI
The Journal of comparative neurology 1990 Dec 22;302(4):992-1001
The Journal of comparative neurology 1990 Dec 22;302(4):992-1001
Peripheral nerve regeneration induces elevated expression of GAP-43 in the brainstem trigeminal complex of adult hamsters.
Erzurumlu RS, Jhaveri S, Moya KL, Benowitz LI
Brain research 1989 Sep 25;498(1):135-9
Brain research 1989 Sep 25;498(1):135-9
Peripheral nerve regeneration induces elevated expression of GAP-43 in the brainstem trigeminal complex of adult hamsters.
Erzurumlu RS, Jhaveri S, Moya KL, Benowitz LI
Brain research 1989 Sep 25;498(1):135-9
Brain research 1989 Sep 25;498(1):135-9
Immunohistochemical localization of GAP-43 in the developing hamster retinofugal pathway.
Moya KL, Jhaveri S, Schneider GE, Benowitz LI
The Journal of comparative neurology 1989 Oct 1;288(1):51-8
The Journal of comparative neurology 1989 Oct 1;288(1):51-8
Anatomical distribution of the growth-associated protein GAP-43/B-50 in the adult rat brain.
Benowitz LI, Apostolides PJ, Perrone-Bizzozero N, Finklestein SP, Zwiers H
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988 Jan;8(1):339-52
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988 Jan;8(1):339-52
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: GAP-43 Antibody [NBP1-41123] - Total protein from Human, Mouse and Rat brain, and SHSY-5Y cells was separated on a 12% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-GAP43 in 1% non-fat milk in TBST and detected with an anti-sheep HRP secondary antibody using chemiluminescence.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: GAP-43 Antibody [NBP1-41123] - Analysis of GAP43 in human brain protein
