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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Immunohistochemistry [1]
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- Product number
- NB100-62239 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-62239, RRID:AB_964979
- Product name
- Mouse Monoclonal Pepsinogen I Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. NB100-62239 recognises human Pepsinogen I, a zymogen or proenzyme secreted by Chief cells in the stomach. It is cleaved to form pepsin both in an autocatalytic fashion and by pepsin itself. In humans there are two related forms of pepsin, Pepsinogen I (also known as pepsinogen A), and Pepsinogen II (also known as Pepsinogen B or progastricsin).
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Immunohistochemistry-Paraffin: Pepsinogen I Antibody (8003 (99/12)) [NB100-62239] - Differentiation of pyloric-gland type to fundic glands. (A) HE-stained image, showing proliferation of atypical glands associated with mildly enlarged nuclei. (B) Differentiation into fundic glands (pepsinogen-1). Tumor glands are positive for pepsinogen-1. (C) Differentiation into fundic glands (H,K-ATPase). Similar to pepsinogen-1, H,K-ATPase-positive cells can be seen in tumor glands. From: Mitsuishi T, Hamatani S, Hirooka S, Fukasawa N, Aizawa D, Hara Y, et al. (2017)
