Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations [0]
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Validation data
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- Product number
- 15880-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- TDO2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TDO2 antibody (Cat. #15880-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Vitamin C and E Treatment Blocks Changes in Kynurenine Metabolism Triggered by Three Weeks of Sprint Interval Training in Recreationally Active Elderly Humans.
Tryptophan catabolism is dysregulated in leiomyomas.
Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy.
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats.
A comprehensive analysis of TDO2 expression in immune cells and characterization of immune cell phenotype in TDO2 knockout mice.
Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells.
Evaluation and comparison of the commonly used bioassays of human indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO).
Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO).
The proatherosclerotic function of indoleamine 2, 3-dioxygenase 1 in the developmental stage of atherosclerosis.
Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation.
Tryptophan 2,3-dioxygenase inhibitory activities of tryptanthrin derivatives.
Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage.
Wyckelsma VL, Trepci A, Schwieler L, Venckunas T, Brazaitis M, Kamandulis S, Paulauskas H, Gapeyeva H, Pääsuke M, Gastaldello S, Imbeault S, Westerblad H, Erhardt S, Andersson DC
Antioxidants (Basel, Switzerland) 2021 Sep 10;10(9)
Antioxidants (Basel, Switzerland) 2021 Sep 10;10(9)
Tryptophan catabolism is dysregulated in leiomyomas.
Chuang TD, Quintanilla D, Boos D, Khorram O
Fertility and sterility 2021 Oct;116(4):1160-1171
Fertility and sterility 2021 Oct;116(4):1160-1171
Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy.
DeVito NC, Sturdivant M, Thievanthiran B, Xiao C, Plebanek MP, Salama AKS, Beasley GM, Holtzhausen A, Novotny-Diermayr V, Strickler JH, Hanks BA
Cell reports 2021 May 4;35(5):109071
Cell reports 2021 May 4;35(5):109071
Tryptophan Pathway-Targeted Metabolomics Study on the Mechanism and Intervention of Cisplatin-Induced Acute Kidney Injury in Rats.
Tan B, Chen J, Qin S, Liao C, Zhang Y, Wang D, Li S, Zhang Z, Zhang P, Xu F
Chemical research in toxicology 2021 Jul 19;34(7):1759-1768
Chemical research in toxicology 2021 Jul 19;34(7):1759-1768
A comprehensive analysis of TDO2 expression in immune cells and characterization of immune cell phenotype in TDO2 knockout mice.
Li S, Li S, Zhao Y, Zhang B, Wang X, Yang X, Wang Y, Jia C, Chang Y, Wei W
Transgenic research 2021 Dec;30(6):781-797
Transgenic research 2021 Dec;30(6):781-797
Salinomycin promotes T-cell proliferation by inhibiting the expression and enzymatic activity of immunosuppressive indoleamine-2,3-dioxygenase in human breast cancer cells.
Ebokaiwe AP, Njoya EM, Sheng Y, Zhang Z, Li S, Zhou Z, Qiang Z, Peng T, Hussein AA, Zhang G, Lu X, Li L, Wang F
Toxicology and applied pharmacology 2020 Oct 1;404:115203
Toxicology and applied pharmacology 2020 Oct 1;404:115203
Evaluation and comparison of the commonly used bioassays of human indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO).
Zhang S, Guo L, Yang D, Xing Z, Li W, Kuang C, Yang Q
Bioorganic chemistry 2020 Nov;104:104348
Bioorganic chemistry 2020 Nov;104:104348
Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO).
Pan S, Zhou Y, Wang Q, Wang Y, Tian C, Wang T, Huang L, Nan J, Li L, Yang S
European journal of medicinal chemistry 2020 Dec 1;207:112703
European journal of medicinal chemistry 2020 Dec 1;207:112703
The proatherosclerotic function of indoleamine 2, 3-dioxygenase 1 in the developmental stage of atherosclerosis.
Liang H, Chen M, Qi F, Shi L, Duan Z, Yang R, He J, Lou B, Li Y, Yang Q
Signal transduction and targeted therapy 2019;4:23
Signal transduction and targeted therapy 2019;4:23
Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation.
Hughey CC, James FD, Wang Z, Goelzer M, Wasserman DH
Molecular metabolism 2019 May;23:1-13
Molecular metabolism 2019 May;23:1-13
Tryptophan 2,3-dioxygenase inhibitory activities of tryptanthrin derivatives.
Zhang S, Qi F, Fang X, Yang D, Hu H, Huang Q, Kuang C, Yang Q
European journal of medicinal chemistry 2018 Dec 5;160:133-145
European journal of medicinal chemistry 2018 Dec 5;160:133-145
Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage.
Tummala KS, Gomes AL, Yilmaz M, Graña O, Bakiri L, Ruppen I, Ximénez-Embún P, Sheshappanavar V, Rodriguez-Justo M, Pisano DG, Wagner EF, Djouder N
Cancer cell 2014 Dec 8;26(6):826-839
Cancer cell 2014 Dec 8;26(6):826-839
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