Antibody data
- Antibody Data
- Antigen structure
- References [5]
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- ELISA [1]
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- Product number
- ABIN394955 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Tryptophan 2,3-Dioxygenase (TDO2) (AA 307-406) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 307-406
- Isotype
- IgG
- Antibody clone number
- 1C8
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children.
Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder.
Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase.
Cooperative binding of L-trp to human tryptophan 2,3-dioxygenase: resonance Raman spectroscopic analysis.
A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase.
Roeske D, Ludwig KU, Neuhoff N, Becker J, Bartling J, Bruder J, Brockschmidt FF, Warnke A, Remschmidt H, Hoffmann P, Müller-Myhsok B, Nöthen MM, Schulte-Körne G
Molecular psychiatry 2011 Jan;16(1):97-107
Molecular psychiatry 2011 Jan;16(1):97-107
Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder.
Miller CL, Murakami P, Ruczinski I, Ross RG, Sinkus M, Sullivan B, Leonard S
Schizophrenia research 2009 Sep;113(2-3):259-67
Schizophrenia research 2009 Sep;113(2-3):259-67
Antimicrobial and immunoregulatory properties of human tryptophan 2,3-dioxygenase.
Schmidt SK, Müller A, Heseler K, Woite C, Spekker K, MacKenzie CR, Däubener W
European journal of immunology 2009 Oct;39(10):2755-64
European journal of immunology 2009 Oct;39(10):2755-64
Cooperative binding of L-trp to human tryptophan 2,3-dioxygenase: resonance Raman spectroscopic analysis.
Fukumura E, Sugimoto H, Misumi Y, Ogura T, Shiro Y
Journal of biochemistry 2009 Apr;145(4):505-15
Journal of biochemistry 2009 Apr;145(4):505-15
A kinetic, spectroscopic, and redox study of human tryptophan 2,3-dioxygenase.
Basran J, Rafice SA, Chauhan N, Efimov I, Cheesman MR, Ghamsari L, Raven EL
Biochemistry 2008 Apr 22;47(16):4752-60
Biochemistry 2008 Apr 22;47(16):4752-60
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