BS8236

antibody from Bioworld Technology, Inc
Targeting: NRBF2 COPR1, COPR2, DKFZp564C1664, FLJ30395
Provider product page for BS8236
Western blot
Immunohistochemistry

Antibody data

Product number
BS8236 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NRBF2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NRBF2.
Description
Nuclear hormone receptors function as transcriptional activators when their cognate ligands are bound. Binding of the appropriate ligand induces a conformational change in the nuclear receptor, allowing it to interact with transcriptional coactivators. NRBF2 (Nuclear receptor-binding factor 2), also known as COPR (Comodulator of PPAR and RXR), is thought to act as a transcriptional coactivator by altering the activity of target nuclear receptors. Highly expressed in the liver, placenta and keratinocytes, NRBF2 can interact with at least 7 nuclear receptors including PPARÏ«, PPARÑ´ and PPARÎÛ. In the presence of a bound ligand, NRBF2 can interact with nuclear receptors RARÏ«, RARÎÛ. and RXRÏ«. NRBF2, which exists as two isoforms due to alternative splicing, is localized to both the nucleus and the cytoplasm.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NRBF2 protein structure - BS8236 shown in red.