BS8236
antibody from Bioworld Technology, Inc
Targeting: NRBF2
COPR1, COPR2, DKFZp564C1664, FLJ30395
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS8236 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- NRBF2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human NRBF2.
- Description
- Nuclear hormone receptors function as transcriptional activators when their cognate ligands are bound. Binding of the appropriate ligand induces a conformational change in the nuclear receptor, allowing it to interact with transcriptional coactivators. NRBF2 (Nuclear receptor-binding factor 2), also known as COPR (Comodulator of PPAR and RXR), is thought to act as a transcriptional coactivator by altering the activity of target nuclear receptors. Highly expressed in the liver, placenta and keratinocytes, NRBF2 can interact with at least 7 nuclear receptors including PPARÏ«, PPARÑ´ and PPARÎÛ. In the presence of a bound ligand, NRBF2 can interact with nuclear receptors RARÏ«, RARÎÛ. and RXRÏ«. NRBF2, which exists as two isoforms due to alternative splicing, is localized to both the nucleus and the cytoplasm.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- WesternBlot (WB) analysis of NRBF2 polyclonal antibody