Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10-7549-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-TOX-3 Antibody
- Antibody type
- Monoclonal
- Description
- TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI).
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant TOX-3
protein (amino acids 232-442) was u
sed as the immunogen for this antib
ody- Isotype
- IgG
- Antibody clone number
- ABM44A1
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of TOX-3. Anti- TOX-3 antibody (Clone: ABM44A1) was tested at 2 µg/ml on (1) PC3, (2) h Testis, (3) HCT-116, (4) h Lung, (5) h Brain, (6) MCF-7 and (7) U87 lysates.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of TOX-3 in human stomach tissue using TOX-3 antibody (Clone: ABM44A1) at 5 µg/ml.
- Protocol
- Protocol