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- Antibody Data
- Antigen structure
- References [7]
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- Western blot [1]
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- Product number
- NB100-61049 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-61049, RRID:AB_2279102
- Product name
- Rabbit Polyclonal Gemin 5 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Bacteria, Porcine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Structural basis for the dimerization of Gemin5 and its role in protein recruitment and translation control.
Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.
The landscape of the non-canonical RNA-binding site of Gemin5 unveils a feedback loop counteracting the negative effect on translation.
The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation.
Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation.
Gemin5 promotes IRES interaction and translation control through its C-terminal region.
Gemin5 proteolysis reveals a novel motif to identify L protease targets.
Moreno-Morcillo M, Francisco-Velilla R, Embarc-Buh A, Fernández-Chamorro J, Ramón-Maiques S, Martinez-Salas E
Nucleic acids research 2020 Jan 24;48(2):788-801
Nucleic acids research 2020 Jan 24;48(2):788-801
Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.
Lampe S, Kunze M, Scholz A, Brauß TF, Winslow S, Simm S, Keller M, Heidler J, Wittig I, Brüne B, Schmid T
Biochimica et biophysica acta. Gene regulatory mechanisms 2018 Feb;1861(2):147-157
Biochimica et biophysica acta. Gene regulatory mechanisms 2018 Feb;1861(2):147-157
The landscape of the non-canonical RNA-binding site of Gemin5 unveils a feedback loop counteracting the negative effect on translation.
Francisco-Velilla R, Fernandez-Chamorro J, Dotu I, Martinez-Salas E
Nucleic acids research 2018 Aug 21;46(14):7339-7353
Nucleic acids research 2018 Aug 21;46(14):7339-7353
The RNA-binding protein Gemin5 binds directly to the ribosome and regulates global translation.
Francisco-Velilla R, Fernandez-Chamorro J, Ramajo J, Martinez-Salas E
Nucleic acids research 2016 Sep 30;44(17):8335-51
Nucleic acids research 2016 Sep 30;44(17):8335-51
Identification of novel non-canonical RNA-binding sites in Gemin5 involved in internal initiation of translation.
Fernandez-Chamorro J, Piñeiro D, Gordon JM, Ramajo J, Francisco-Velilla R, Macias MJ, Martinez-Salas E
Nucleic acids research 2014 May;42(9):5742-54
Nucleic acids research 2014 May;42(9):5742-54
Gemin5 promotes IRES interaction and translation control through its C-terminal region.
Piñeiro D, Fernández N, Ramajo J, Martínez-Salas E
Nucleic acids research 2013 Jan;41(2):1017-28
Nucleic acids research 2013 Jan;41(2):1017-28
Gemin5 proteolysis reveals a novel motif to identify L protease targets.
Piñeiro D, Ramajo J, Bradrick SS, Martínez-Salas E
Nucleic acids research 2012 Jun;40(11):4942-53
Nucleic acids research 2012 Jun;40(11):4942-53
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Gemin 5 Antibody [NB100-61049] - Detection of Human Gemin5 on HeLa whole cell lysate using NB100-61049. Gemin5 was also immunoprecipitated by rabbit anti-Gemin5 antibody NB100-61048.
