APR06929G

antibody from Leading Biology

Targeting: SUSD3 MGC26847

Western blot (Recommended by provider)

Antibody Data

Product number

APR06929G

Provider

Leading Biology

Product name

SUSD3 Antibody

Antibody type

Polyclonal

Description

Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.