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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunohistochemistry [3]
- Flow cytometry [3]
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- Product number
- NB300-576 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB300-576, RRID:AB_10000921
- Product name
- Mouse Monoclonal p23/PTGES3 Antibody
- Antibody type
- Monoclonal
- Description
- Unpurified. p23 (JJ3)
- Reactivity
- Human, Mouse, Rat, Chicken/Avian, Guinea Pig, Rabbit, Simian, Xenopus
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100uL
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co-chaperone STI1.
Proteostasis regulators as potential rescuers of PMM2 activity.
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
Caspase-activated DNase is necessary and sufficient for oligonucleosomal DNA breakdown, but not for chromatin disassembly during caspase-dependent apoptosis of LN-18 glioblastoma cells.
NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w.
Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease.
Lackie RE, Razzaq AR, Farhan SMK, Qiu LR, Moshitzky G, Beraldo FH, Lopes MH, Maciejewski A, Gros R, Fan J, Choy WY, Greenberg DS, Martins VR, Duennwald ML, Lerch JP, Soreq H, Prado VF, Prado MAM
Journal of neurochemistry 2020 Jun;153(6):727-758
Journal of neurochemistry 2020 Jun;153(6):727-758
Proteostasis regulators as potential rescuers of PMM2 activity.
Vilas A, Yuste-Checa P, Gallego D, Desviat LR, Ugarte M, Pérez-Cerda C, Gámez A, Pérez B
Biochimica et biophysica acta. Molecular basis of disease 2020 Jul 1;1866(7):165777
Biochimica et biophysica acta. Molecular basis of disease 2020 Jul 1;1866(7):165777
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
Garcia-Belinchón M, Sánchez-Osuna M, Martínez-Escardó L, Granados-Colomina C, Pascual-Guiral S, Iglesias-Guimarais V, Casanelles E, Ribas J, Yuste VJ
The Journal of biological chemistry 2015 Aug 21;290(34):20841-20855
The Journal of biological chemistry 2015 Aug 21;290(34):20841-20855
Caspase-activated DNase is necessary and sufficient for oligonucleosomal DNA breakdown, but not for chromatin disassembly during caspase-dependent apoptosis of LN-18 glioblastoma cells.
Sánchez-Osuna M, Garcia-Belinchón M, Iglesias-Guimarais V, Gil-Guiñón E, Casanelles E, Yuste VJ
The Journal of biological chemistry 2014 Jul 4;289(27):18752-69
The Journal of biological chemistry 2014 Jul 4;289(27):18752-69
NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w.
Casanelles E, Gozzelino R, Marqués-Fernández F, Iglesias-Guimarais V, Garcia-Belinchón M, Sánchez-Osuna M, Solé C, Moubarak RS, Comella JX, Yuste VJ
Biochimica et biophysica acta 2013 May;1833(5):1085-95
Biochimica et biophysica acta 2013 May;1833(5):1085-95
Apoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonuclease.
Iglesias-Guimarais V, Gil-Guiñon E, Gabernet G, García-Belinchón M, Sánchez-Osuna M, Casanelles E, Comella JX, Yuste VJ
The Journal of biological chemistry 2012 Mar 2;287(10):7766-79
The Journal of biological chemistry 2012 Mar 2;287(10):7766-79
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: p23/PTGES3 Antibody (JJ3) [NB300-576] - Analysis of 25 ug of Hela (Lane 1), HepG2 (Lane 2), and mouse spleen cell lysates (Lane 3) and a molecular weight protein ladder.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: p23/PTGES3 Antibody (JJ3) [NB300-576] - Cancer biopsies of deparaffinized Human breast carcinoma tissue.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: p23/PTGES3 Antibody (JJ3) [NB300-576] - Normal biopsies of deparaffinized Human tonsil tissue.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: p23/PTGES3 Antibody (JJ3) [NB300-576] - Normal biopsies of deparaffinized Human testis tissue.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: p23/PTGES3 Antibody (JJ3) [NB300-576] - Analysis of Jurkat cells compared to an isotype control (blue).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: p23/PTGES3 Antibody (JJ3) [NB300-576] - Analysis of Hela cells compared to an isotype control (blue).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: p23/PTGES3 Antibody (JJ3) [NB300-576] - Analysis of 3T3 cells compared to an isotype control (blue).
