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LearnBS60489
antibody from Bioworld Technology, Inc
Targeting: MIEN1
C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60489 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- MIEN1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human MIEN1.
- Description
- C35, also known as XTP4 (HBV X-transactivated gene 4) and protein C17orf37, is a 115 amino acid cytoplasmic protein that is a member of the SelWTH protein family. SelWTH proteins contain a thioredoxin-like fold and a conserved CxxC or CxxU motif, suggesting that they may play functional role in redox reactions. Although found at trace levels in normal breast ductal epithelium and testis, expression of C35 is robust in infiltrating ductal carcinomas of the breast, lobular carcinoma, as well as distant metastases of breast cancer such as liver, lung and skin. The prevalence and abundance of C35 overexpression in tumors suggest that it may be an appropriate bio-marker for diagnosis and a potential target for therapeutic intervention.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of MIEN1 pAb at 1:500 dilutionLane1:MCF-7 whole cell lysateLane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate
