Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB2330 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2330, RRID:AB_10549763
- Product name
- BEST1 monoclonal antibody, clone E6-6
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against synthetic peptide of BEST1.
- Antigen sequence
KDHMDPYWALENRDEAHS
- Isotype
- IgG
- Antibody clone number
- E6-6
- Storage
- Store at -20°C or -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Derivation and comparative assessment of retinal pigment epithelium from human embryonic stem cells using transcriptomics.
Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium.
Bestrophin gene mutations in patients with Best vitelliform macular dystrophy.
Identification of the gene responsible for Best macular dystrophy.
Klimanskaya I, Hipp J, Rezai KA, West M, Atala A, Lanza R
Cloning and stem cells 2004;6(3):217-45
Cloning and stem cells 2004;6(3):217-45
Bestrophin, the product of the Best vitelliform macular dystrophy gene (VMD2), localizes to the basolateral plasma membrane of the retinal pigment epithelium.
Marmorstein AD, Marmorstein LY, Rayborn M, Wang X, Hollyfield JG, Petrukhin K
Proceedings of the National Academy of Sciences of the United States of America 2000 Nov 7;97(23):12758-63
Proceedings of the National Academy of Sciences of the United States of America 2000 Nov 7;97(23):12758-63
Bestrophin gene mutations in patients with Best vitelliform macular dystrophy.
Caldwell GM, Kakuk LE, Griesinger IB, Simpson SA, Nowak NJ, Small KW, Maumenee IH, Rosenfeld PJ, Sieving PA, Shows TB, Ayyagari R
Genomics 1999 May 15;58(1):98-101
Genomics 1999 May 15;58(1):98-101
Identification of the gene responsible for Best macular dystrophy.
Petrukhin K, Koisti MJ, Bakall B, Li W, Xie G, Marknell T, Sandgren O, Forsman K, Holmgren G, Andreasson S, Vujic M, Bergen AA, McGarty-Dugan V, Figueroa D, Austin CP, Metzker ML, Caskey CT, Wadelius C
Nature genetics 1998 Jul;19(3):241-7
Nature genetics 1998 Jul;19(3):241-7
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of BEST1 (68 kDa) from human RPE cell lysate using BEST1 monoclonal antibody, clone E6-6 (Cat # MAB2330) (1 : 1000).