Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B9850 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human BEST1 monoclonal antibody, clone F77
- Antibody type
- Monoclonal
- Description
- This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- F77
- Vial size
- 100 _l
- Storage
- Store at -20°C or -80°C.
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