BS7983

antibody from Bioworld Technology, Inc

Targeting: AKTIP FLJ13258, FTS

Immunohistochemistry

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Validation data

Product number: BS7983 - Provider product page
Provider: Bioworld Technology, Inc
Product name: AKTIP polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human AKTIP.
Description: Fused toes protein homolog (FTS), also known as AKT-interacting protein (AKTIP) and Ft1, is a 292 amino acid protein that localizes to the cytoplasm and the cell membrane. A member of the ubiquitin-conjugating enzyme family, FTS binds directly to AKT1 to regulate apoptosis in a cell population. AKT1 is a protein that plays a critical role in a number of cellular responses, such as cell growth, protein synthesis, and antiapoptotic signaling. The interaction of FTS and AKT1 enhances the phosphorylation and activation of AKT1, which, through an AKT1/GSK-3ÉÇ/NFATc1 signaling cascade, results in the increased production of the proapoptotic hormone Fas ligand and thus an increase in apoptosis.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

AKTIP protein structure - BS7983 shown in red.