Tissue expression
Cell line expression
Protein structure
FTO
FTO alpha-ketoglutarate dependent dioxygenaseALKBH9, KIAA1752, MGC5149
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
Top validated antibodies |
|||||
NSJ Bioreagents | ![]() |
Polyclonal |
|
||
Proteintech Group | ![]() |
132 references | Polyclonal |
|
|
GeneTex | ![]() |
1 references | Polyclonal |
|
|
LSBio | ![]() |
Polyclonal |
|
||
antibodies-online | ![]() |
1 references | Polyclonal |
|