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- References [4]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 14649-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14649-1-AP, RRID:AB_2187290
- Product name
- POSH antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated POSH antibody (Cat. #14649-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions.
The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia.
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia.
Goodwani S, Fernandez C, Acton PJ, Buggia-Prevot V, McReynolds ML, Ma J, Hu CH, Hamby ME, Jiang Y, Le K, Soth MJ, Jones P, Ray WJ
International journal of molecular sciences 2020 Jul 9;21(14)
International journal of molecular sciences 2020 Jul 9;21(14)
The pro-apoptotic JNK scaffold POSH/SH3RF1 mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia.
West RJH, Ugbode C, Gao FB, Sweeney ST
Human molecular genetics 2018 Apr 15;27(8):1382-1395
Human molecular genetics 2018 Apr 15;27(8):1382-1395
POSH participates in epileptogenesis by increasing the surface expression of the NMDA receptor: a promising therapeutic target for epilepsy.
Wang X, Tian X, Yang Y, Lu X, Li Y, Ma Y, Zhang Y, Zheng F, Lu S, Xu D, Xu X, Wang W, Wang X
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
Expert opinion on therapeutic targets 2017 Dec;21(12):1083-1094
Rab8, POSH, and TAK1 regulate synaptic growth in a Drosophila model of frontotemporal dementia.
West RJ, Lu Y, Marie B, Gao FB, Sweeney ST
The Journal of cell biology 2015 Mar 30;208(7):931-47
The Journal of cell biology 2015 Mar 30;208(7):931-47
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 14649-1-AP(SH3RF1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 14649-1-AP(SH3RF1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SH3RF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SH3RF1. This antibody recognizes human, mouse, rat antigen. The SH3RF1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
