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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 20392-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20392-1-AP, RRID:AB_10693618
- Product name
- STAC3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated STAC3 antibody (Cat. #20392-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Preconditioning contractions prevent prolonged force depression and Ca2+-dependent proteolysis of STAC3 after damaging eccentric contractions.
Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
STAC3 variants cause a congenital myopathy with distinctive dysmorphic features and malignant hyperthermia susceptibility.
STAC3 incorporation into skeletal muscle triads occurs independent of the dihydropyridine receptor.
The SH3 and cysteine-rich domain 3 (Stac3) gene is important to growth, fiber composition, and calcium release from the sarcoplasmic reticulum in postnatal skeletal muscle.
Ashida Y, Himori K, Tamai K, Kimura I, Yamada T
Journal of applied physiology (Bethesda, Md. : 1985) 2021 Nov 1;131(5):1399-1407
Journal of applied physiology (Bethesda, Md. : 1985) 2021 Nov 1;131(5):1399-1407
Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling.
Rufenach B, Christy D, Flucher BE, Bui JM, Gsponer J, Campiglio M, Van Petegem F
Structure (London, England : 1993) 2020 Aug 4;28(8):922-932.e5
Structure (London, England : 1993) 2020 Aug 4;28(8):922-932.e5
STAC3 variants cause a congenital myopathy with distinctive dysmorphic features and malignant hyperthermia susceptibility.
Zaharieva IT, Sarkozy A, Munot P, Manzur A, O'Grady G, Rendu J, Malfatti E, Amthor H, Servais L, Urtizberea JA, Neto OA, Zanoteli E, Donkervoort S, Taylor J, Dixon J, Poke G, Foley AR, Holmes C, Williams G, Holder M, Yum S, Medne L, Quijano-Roy S, Romero NB, Fauré J, Feng L, Bastaki L, Davis MR, Phadke R, Sewry CA, Bönnemann CG, Jungbluth H, Bachmann C, Treves S, Muntoni F
Human mutation 2018 Dec;39(12):1980-1994
Human mutation 2018 Dec;39(12):1980-1994
STAC3 incorporation into skeletal muscle triads occurs independent of the dihydropyridine receptor.
Campiglio M, Kaplan MM, Flucher BE
Journal of cellular physiology 2018 Dec;233(12):9045-9051
Journal of cellular physiology 2018 Dec;233(12):9045-9051
The SH3 and cysteine-rich domain 3 (Stac3) gene is important to growth, fiber composition, and calcium release from the sarcoplasmic reticulum in postnatal skeletal muscle.
Cong X, Doering J, Mazala DA, Chin ER, Grange RW, Jiang H
Skeletal muscle 2016;6:17
Skeletal muscle 2016;6:17
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 20392-1-AP(STAC3 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 20392-1-AP(STAC3 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STAC3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human STAC3. This antibody recognizes human, mouse, rat antigen. The STAC3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
