Antibody data

Product number
BS9124 - Provider product page
Provider
Bioworld Technology, Inc
Product name
FOXH1 (Q19) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to the N-terminal of Human FOXH1.
Description
The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states. FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4. Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues. FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGÉÇ and activin, indicating that these FAST proteins mediate TFGÉÇ induced signal transduction.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
FOXH1 protein structure - BS9124 shown in red.