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- References [3]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- NBP1-52300 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-52300, RRID:AB_11027699
- Product name
- Rabbit Polyclonal DNA Polymerase gamma Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Human DNA polymerase gamma. Predicted cross-reactivity based on amino acid sequence homology: mouse (91%), rat (91%).
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.05 ml
- Concentration
- 0.67 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Valproic acid-induced hepatotoxicity in Alpers syndrome is associated with mitochondrial permeability transition pore opening-dependent apoptotic sensitivity in an induced pluripotent stem cell model.
Subnormal levels of POLγA cause inefficient initiation of light-strand DNA synthesis and lead to mitochondrial DNA deletions and progressive external ophthalmoplegia [corrected].
Mitochondrial DNA base excision repair and mitochondrial DNA mutation in human hepatic HuH-7 cells exposed to stavudine.
Li S, Guo J, Ying Z, Chen S, Yang L, Chen K, Long Q, Qin D, Pei D, Liu X
Hepatology (Baltimore, Md.) 2015 May;61(5):1730-9
Hepatology (Baltimore, Md.) 2015 May;61(5):1730-9
Subnormal levels of POLγA cause inefficient initiation of light-strand DNA synthesis and lead to mitochondrial DNA deletions and progressive external ophthalmoplegia [corrected].
Roos S, Macao B, Fusté JM, Lindberg C, Jemt E, Holme E, Moslemi AR, Oldfors A, Falkenberg M
Human molecular genetics 2013 Jun 15;22(12):2411-22
Human molecular genetics 2013 Jun 15;22(12):2411-22
Mitochondrial DNA base excision repair and mitochondrial DNA mutation in human hepatic HuH-7 cells exposed to stavudine.
Wu Y, Li N, Zhang T, Wu H, Huang C, Chen D
Mutation research 2009 May 12;664(1-2):28-38
Mutation research 2009 May 12;664(1-2):28-38
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DNA Polymerase gamma Antibody [NBP1-52300] - Analysis of anti-POLG antibody with (30 ug of whole cell lysate). A: 293T. 5% SDS PAGE. POLG antibody diluted at 1:5000.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DNA Polymerase gamma Antibody [NBP1-52300] - Analysis of anti-POLG antibody with human skeletal muscle at concentration 10 ug/ml.
