Tissue expression
Cell line expression
Protein structure
CENPI
Centromere protein ICENP-I, FSHPRH1, LRPR1, Mis6
This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. [provided by RefSeq, Jan 2016]
Top validated antibodies |
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Biorbyt | ![]() |
Polyclonal |
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NSJ Bioreagents | ![]() |
Polyclonal |
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antibodies-online | ![]() |
3 references | Polyclonal |
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Affinity Biosciences | ![]() |
Polyclonal |
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LSBio | ![]() |
Polyclonal |
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