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- Antigen structure
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- Product number
- ABIN393305 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Dynactin 2 (p50) (DCTN2) (AA 302-401) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 302-401
- Isotype
- IgG
- Antibody clone number
- 2G7
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Molecular and functional basis for the scaffolding role of the p50/dynamitin subunit of the microtubule-associated dynactin complex.
Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes.
N-terminal region of ZW10 serves not only as a determinant for localization but also as a link with dynein function.
Dynamitin mutagenesis reveals protein-protein interactions important for dynactin structure.
GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome.
Jacquot G, Maidou-Peindara P, Benichou S
The Journal of biological chemistry 2010 Jul 23;285(30):23019-31
The Journal of biological chemistry 2010 Jul 23;285(30):23019-31
Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes.
Pridgeon JW, Webber EA, Sha D, Li L, Chin LS
The FEBS journal 2009 Jan;276(1):118-31
The FEBS journal 2009 Jan;276(1):118-31
N-terminal region of ZW10 serves not only as a determinant for localization but also as a link with dynein function.
Inoue M, Arasaki K, Ueda A, Aoki T, Tagaya M
Genes to cells : devoted to molecular & cellular mechanisms 2008 Aug;13(8):905-14
Genes to cells : devoted to molecular & cellular mechanisms 2008 Aug;13(8):905-14
Dynamitin mutagenesis reveals protein-protein interactions important for dynactin structure.
Maier KC, Godfrey JE, Echeverri CJ, Cheong FK, Schroer TA
Traffic (Copenhagen, Denmark) 2008 Apr;9(4):481-91
Traffic (Copenhagen, Denmark) 2008 Apr;9(4):481-91
GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome.
Fumoto K, Hoogenraad CC, Kikuchi A
The EMBO journal 2006 Dec 13;25(24):5670-82
The EMBO journal 2006 Dec 13;25(24):5670-82
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