abx011689

PSMB8 antibody from Abbexa
beta5i, D6S216E, LMP7, PSMB5i, RING10
Western blot
Recommended by provider
ELISA
Recommended by provider
Immunocytochemistry
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
abx011689
Provider
Abbexa
Product name
Proteasome Subunit Beta Type 8 (PSMB8) Antibody
Provider product page
Abbexa - abx011689
Antibody type
Monoclonal
Description
Proteasome Subunit Beta Type 8 (PSMB8) Antibody is a Mouse Monoclonal against Proteasome Subunit Beta Type 8 (PSMB8) Antibody. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 3 (proteasome beta 5 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit. Two alternative transcripts encoding two isoforms have been identified; both isoforms are processed to yield the same mature subunit.
Reactivity
Human, Rat
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 µl
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Provider Type Product Number
- No reagents -