BS7229

antibody from Bioworld Technology, Inc
Targeting: USP7 HAUSP
Provider product page for BS7229
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS7229 - Provider product page
Provider
Bioworld Technology, Inc
Product name
USP7 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human USP7.
Description
Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzyme (DUB) action. Five DUB subfamilies are recognized, including the USP, UCH, OTU, MJD and JAMM enzymes. Herpesvirus-associated ubiquitin-specific protease (HAUSP, USP7) is an important deubiquitinase belonging to USP subfamily. A key HAUSP function is to bind and deubiquitinate the p53 transcription factor and an associated regulator protein Mdm2, thereby stabilizing both proteins. In addition to regulating essential components of the p53 pathway, HAUSP also modifies other ubiquitinylated proteins such as members of the FoxO family of forkhead transcription factors and the mitotic stress checkpoint protein CHFR.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
USP7 protein structure - BS7229 shown in red.