Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Immunoelectron microscopy [1]
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Validation data
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- Product number
- 621002 - Provider product page
- Provider
- BioLegend
- Product name
- Purified anti-GRASP65
- Antibody type
- Polyclonal
- Antigen
- Recombinant (partial)
- Description
- GRASP65 (golgi reassembly stacking protein 1, Golgi peripheral membrane protein p65, reassembly and stacking protein p65) is a 65 kD Golgi stacking protein. Alternatively spliced transcripts of GRASP65 have been identified. This protein is thought to play a role in establishing the stacked structure of the Golgi cisternae allowing sorting and modification of proteins exported from the endoplasmic reticulum. GRASP65 is cleaved by caspase-3 during apoptosis and can be partitioned by fragmentation and dispersal during entry into mitosis. GRASP65 is modified by phosphorylation (polo-like kinase-1 and cdc2-cyclin B). This protein has been shown to form a complex with the Golgi matrix protein GOLGA2; this complex then interacts with the vesicle docking protein p115,and tethering factor GM130.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Vial size
- 200 µl
- Storage
- Upon receipt, store frozen at -20° C.
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- A549 (upper panel) and Vero E6 (lower panel) cells stained with purified rabbit anti-GRASP65, followed by Cy3-conjugated goat anti-rabbit IgG and DAPI.
- Conjugate
- Unconjugated