328204

antibody from BioLegend

Targeting: ENTPD1 ATPDase, CD39, NTPDase-1, SPG64

Immunohistochemistry (Recommended by provider)

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

328204

Provider

BioLegend

Proper citation

BioLegend Cat#328204, RRID:AB_940433

Product name

Biotin anti-human CD39

Antibody type

Monoclonal

Antigen

PHA activated human lymphocytes

Description

Human CD39 is an integral membrane protein with two transmembrane domains and exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. Recently, CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.

Reactivity

Human, Simian

Host

Mouse

Conjugate

Biotin

Isotype

IgG

Vial size

100 µg

Concentration

0.5 mg/ml

Storage

The antibody solution should be stored undiluted at 4°C. Do not freeze.

Flow cytometry

Supportive validation

Submitted by

BioLegend (provider)

Main image

Experimental details

Human peripheral blood lymphocytes stained with biotinylated A1, followed by Sav-PE

Conjugate

Biotin