BS9189

antibody from Bioworld Technology, Inc

Targeting: STK10 LOK, PRO2729

Western blot (Data presented on provider website)

Antibody Data

Product number

BS9189

Provider

Bioworld Technology, Inc

Product name

LOK (T530) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 501-550 of Human LOK.

Description

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/ threonine (Ser/Thr) protein kinases. LOK (lymphocyte-oriented kinase), also known as STK10 (serine/threonine kinase 10), is a 968 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed in lymphoid organs, LOK functions to catalyze the ATP-dependent phosphorylation of target proteins, such as MBP (myelin basic protein) and Histone H2A, thereby playing a role in signaling pathways throughout the cell.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.