Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11-12023 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-NKX2-5 Antibody
- Antibody type
- Polyclonal
- Description
- Cardiac-specific Nkx2-5 is a member of the NK2 family of homeodomain-containing transcription factors, and its expression and functions overlap with those of GATA4, GATA5, and GATA6 during cardiovascular genesis, especially in the regulation of target gene expression synergistically with GATA4, which justifies screening for Nkx2-5 as a prime candidate gene for idiopathic AF (Atrial Fibrillation). NKX2-5 plays an important role in heart formation and development. Moreover, NKX2-5 not only individually acts in transcriptional regulation, but also interacts with other transcription factors in the early stage of cardiac development.
- Reactivity
- Human
- Host
- Rabbit
- Antigen sequence
A partial length recombinant NKX2-5
protein (amino acids 102-324) was
used as the immunogen for this anti
body.- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
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Supportive validation
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- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Expression analysis of NKX2-5. Anti-NKX2-5 antibody (11-12023) was used at 2 µg/ml on MCF-7 lysate.