BS8087

antibody from Bioworld Technology, Inc
Targeting: CHD2 DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614
Provider product page for BS8087
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8087 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CHD2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CHD2.
Description
The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD proteins alter gene expression by modifying chromatin structure,thereby altering access of the transcriptional machinery to its chromosomal DNA template. Chromodomain helicase DNA binding protein 2, also known as CHD2, is a member of the SNF2/RAD54 helicase family of chromatin remodeling and DNA-binding proteins (CDH proteins). Consisting of 1,828 amino acids, CHD2 is expressed in the nucleus and contains two chromo domains, a helicase ATP-binding domain and a helicase C-terminal domain. CHD2 is suggested to play a critical role in development, hematopoiesis and tumor suppression. Mutations in the gene encoding CHD2 may be the cause of glomerulopathy, proteinuria and significantly impaired kidney function. CHD2 exists as two alternatively spliced isoforms.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CHD2 protein structure - BS8087 shown in red.