Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 16251-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16251-1-AP, RRID:AB_2262469
- Product name
- FAF2 antibody
- Antibody type
- Polyclonal
- Description
- FAF2 antibody (Cat. #16251-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner.
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation.
gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.
USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation.
Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation.
A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation.
Gwon Y, Maxwell BA, Kolaitis RM, Zhang P, Kim HJ, Taylor JP
Science (New York, N.Y.) 2021 Jun 25;372(6549):eabf6548
Science (New York, N.Y.) 2021 Jun 25;372(6549):eabf6548
A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates.
Huang EY, To M, Tran E, Dionisio LTA, Cho HJ, Baney KLM, Pataki CI, Olzmann JA
Molecular biology of the cell 2018 May 1;29(9):1021-1030
Molecular biology of the cell 2018 May 1;29(9):1021-1030
The VCP-UBXN1 Complex Mediates Triage of Ubiquitylated Cytosolic Proteins Bound to the BAG6 Complex.
Ganji R, Mukkavalli S, Somanji F, Raman M
Molecular and cellular biology 2018 Jul 1;38(13)
Molecular and cellular biology 2018 Jul 1;38(13)
Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation.
To M, Peterson CW, Roberts MA, Counihan JL, Wu TT, Forster MS, Nomura DK, Olzmann JA
Molecular biology of the cell 2017 Jan 15;28(2):270-284
Molecular biology of the cell 2017 Jan 15;28(2):270-284
gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.
Zhang T, Xu Y, Liu Y, Ye Y
Molecular biology of the cell 2015 Dec 1;26(24):4438-50
Molecular biology of the cell 2015 Dec 1;26(24):4438-50
USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation.
Liu Y, Soetandyo N, Lee JG, Liu L, Xu Y, Clemons WM Jr, Ye Y
eLife 2014;3:e01369
eLife 2014;3:e01369
Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation.
Lee JG, Kim W, Gygi S, Ye Y
The Journal of biological chemistry 2014 Feb 7;289(6):3510-7
The Journal of biological chemistry 2014 Feb 7;289(6):3510-7
A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation.
Xu Y, Liu Y, Lee JG, Ye Y
The Journal of biological chemistry 2013 Jun 21;288(25):18068-76
The Journal of biological chemistry 2013 Jun 21;288(25):18068-76
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 16251-1-AP(FAF2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-FAF2 (IP:16251-1-AP, 3ug; Detection:16251-1-AP 1:1000) with mouse brain tissue lysate 5000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FAF2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FAF2. This antibody recognizes human,mouse,rat antigen. The FAF2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
