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- Antibody Data
- Antigen structure
- References [16]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 12125-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12125-1-AP, RRID:AB_2173765
- Product name
- RAB22A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAB22A antibody (Cat. #12125-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TBC1D24 regulates recycling of clathrin-independent cargo proteins mediated by tubular recycling endosomes.
Exosome-mediated delivery of miR-204-5p inhibits tumor growth and chemoresistance.
Rab22a is a novel prognostic marker for cell progression in breast cancer.
Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs.
An ARF6-Exportin-5 axis delivers pre-miRNA cargo to tumour microvesicles.
Rab22A recruits BLOC-1 and BLOC-2 to promote the biogenesis of recycling endosomes.
The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6.
Human liver cell trafficking mutants: characterization and whole exome sequencing.
Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.
Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells.
New target genes of MITF-induced microRNA-211 contribute to melanoma cell invasion.
A specific subset of RabGTPases controls cell surface exposure of MT1-MMP, extracellular matrix degradation and three-dimensional invasion of macrophages.
Rab22 controls NGF signaling and neurite outgrowth in PC12 cells.
Epigenetic silencing of microRNA-373 plays an important role in regulating cell proliferation in colon cancer.
Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.
Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis.
Kim Nguyen NT, Ohbayashi N, Kanaho Y, Funakoshi Y
Biochemical and biophysical research communications 2020 Jul 12;528(1):220-226
Biochemical and biophysical research communications 2020 Jul 12;528(1):220-226
Exosome-mediated delivery of miR-204-5p inhibits tumor growth and chemoresistance.
Yao S, Yin Y, Jin G, Li D, Li M, Hu Y, Feng Y, Liu Y, Bian Z, Wang X, Mao Y, Zhang J, Wu Z, Huang Z
Cancer medicine 2020 Aug;9(16):5989-5998
Cancer medicine 2020 Aug;9(16):5989-5998
Rab22a is a novel prognostic marker for cell progression in breast cancer.
He M, Shen L, Jiang C, Gao G, Wang K, Jiao Y, Sun L, Cui Y, Ke Z, Yang Z
International journal of molecular medicine 2020 Apr;45(4):1037-1046
International journal of molecular medicine 2020 Apr;45(4):1037-1046
Hypoxia preconditioned renal tubular epithelial cell-derived extracellular vesicles alleviate renal ischaemia-reperfusion injury mediated by the HIF-1α/Rab22 pathway and potentially affected by microRNAs.
Zhang L, Liu H, Xu K, Ling Z, Huang Y, Hu Q, Lu K, Liu C, Wang Y, Liu N, Zhang X, Xu B, Wu J, Chen S, Zhang G, Chen M
International journal of biological sciences 2019;15(6):1161-1176
International journal of biological sciences 2019;15(6):1161-1176
An ARF6-Exportin-5 axis delivers pre-miRNA cargo to tumour microvesicles.
Clancy JW, Zhang Y, Sheehan C, D'Souza-Schorey C
Nature cell biology 2019 Jul;21(7):856-866
Nature cell biology 2019 Jul;21(7):856-866
Rab22A recruits BLOC-1 and BLOC-2 to promote the biogenesis of recycling endosomes.
Shakya S, Sharma P, Bhatt AM, Jani RA, Delevoye C, Setty SR
EMBO reports 2018 Dec;19(12)
EMBO reports 2018 Dec;19(12)
The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6.
Yin Y, Yao S, Hu Y, Feng Y, Li M, Bian Z, Zhang J, Qin Y, Qi X, Zhou L, Fei B, Zou J, Hua D, Huang Z
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Dec 1;23(23):7375-7387
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Dec 1;23(23):7375-7387
Human liver cell trafficking mutants: characterization and whole exome sequencing.
Yuan F, Snapp EL, Novikoff PM, Suadicani SO, Spray DC, Potvin B, Wolkoff AW, Stanley P
PloS one 2014;9(1):e87043
PloS one 2014;9(1):e87043
Identification of genetic loci associated with primary angle-closure glaucoma in the basset hound.
Ahram DF, Cook AC, Kecova H, Grozdanic SD, Kuehn MH
Molecular vision 2014;20:497-510
Molecular vision 2014;20:497-510
Characterization of intracellular dynamics of inoculated PrP-res and newly generated PrP(Sc) during early stage prion infection in Neuro2a cells.
Yamasaki T, Baron GS, Suzuki A, Hasebe R, Horiuchi M
Virology 2014 Feb;450-451:324-35
Virology 2014 Feb;450-451:324-35
New target genes of MITF-induced microRNA-211 contribute to melanoma cell invasion.
Margue C, Philippidou D, Reinsbach SE, Schmitt M, Behrmann I, Kreis S
PloS one 2013;8(9):e73473
PloS one 2013;8(9):e73473
A specific subset of RabGTPases controls cell surface exposure of MT1-MMP, extracellular matrix degradation and three-dimensional invasion of macrophages.
Wiesner C, El Azzouzi K, Linder S
Journal of cell science 2013 Jul 1;126(Pt 13):2820-33
Journal of cell science 2013 Jul 1;126(Pt 13):2820-33
Rab22 controls NGF signaling and neurite outgrowth in PC12 cells.
Wang L, Liang Z, Li G
Molecular biology of the cell 2011 Oct;22(20):3853-60
Molecular biology of the cell 2011 Oct;22(20):3853-60
Epigenetic silencing of microRNA-373 plays an important role in regulating cell proliferation in colon cancer.
Tanaka T, Arai M, Wu S, Kanda T, Miyauchi H, Imazeki F, Matsubara H, Yokosuka O
Oncology reports 2011 Nov;26(5):1329-35
Oncology reports 2011 Nov;26(5):1329-35
Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.
Seto S, Tsujimura K, Koide Y
Traffic (Copenhagen, Denmark) 2011 Apr;12(4):407-20
Traffic (Copenhagen, Denmark) 2011 Apr;12(4):407-20
Rabex-5 is a Rab22 effector and mediates a Rab22-Rab5 signaling cascade in endocytosis.
Zhu H, Liang Z, Li G
Molecular biology of the cell 2009 Nov;20(22):4720-9
Molecular biology of the cell 2009 Nov;20(22):4720-9
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 12125-1-AP(RAB22A antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-RAB22A (IP:12125-1-AP, 3ug; Detection:12125-1-AP 1:300) with COLO 320 cells lysate 1720ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAB22A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAB22A. This antibody recognizes human,mouse,rat antigen. The RAB22A antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
