Tissue expression
Cell line expression
Protein structure
ASCC1
Activating signal cointegrator 1 complex subunit 1ASC1p50, CGI-18, Em:AC022392.3, p50
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Top validated antibodies |
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Invitrogen Antibodies | CF503721 | Monoclonal |
WB
ICC
IHC
FC |
||
OriGene | TA503721 | Monoclonal |
WB
ICC
IHC
FC |
||
antibodies-online | ABIN4281836 | Monoclonal |
WB
ICC
IHC
FC |
||
Novus Biologicals | NBP2-01345 | Monoclonal |
WB
ICC
IHC
FC |
||
Proteintech Group | 12301-1-AP | 3 references | Polyclonal |
WB
EL |
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