FNab07228

antibody from FineTest Biotech
Targeting: DDIT4 Dig2, FLJ20500, REDD-1, REDD1, RTP801
Provider product page for FNab07228
Western blot
ELISA
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
FNab07228 - Provider product page
Provider
FineTest Biotech
Product name
REDD1 specific antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
REDD1, also named as RTP801 and DDIT4, belongs to the DDIT4 family.Its function£ºRegulates cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1(mTORC1). Inhibition of mTORC1 is mediated by a pathway that involves DDIT4/REDD1, AKT1, the TSC1-TSC2 complex and the GTPase RHEB. Plays an important role in responses to cellular energy levels and cellular stress, including responses to hypoxia and DNA damage. Regulates p53/TP53-mediated apoptosis in response to DNA damage via its effect on mTORC1 activity. Its role in the response to hypoxia depends on the cell type; it mediates mTORC1 inhibition in fibroblasts and thymocytes, but not in hepatocytes(By similarity). Required for mTORC1-mediated defense against viral protein synthesis and virus replication(By similarity). Inhibits neuronal differentiation and neurite outgrowth mediated by NGF via its effect on mTORC1 activity. Required for normal neuron migration during embryonic brain development. Plays a role in neuronal cell death.This antibody is specific to the REDD1.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
DNA-damage-inducible transcript 4
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
DDIT4 protein structure - FNab07228 shown in red.