Antibody data
- Antibody Data
- Antigen structure
- References [31]
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- Validations
- Immunohistochemistry [1]
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- Product number
- ABIN617912 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-5-Hydroxytryptamine (serotonin) Receptor 2A, G Protein-Coupled (HTR2A) (AA 22-41) antibody
- Antibody type
- Polyclonal
- Antigen
- Rat 5HT2A receptor (22-41) MAP
- Description
- Affinity Purified
- Reactivity
- Human, Mouse, Rat, Rabbit
- Host
- Rabbit
- Epitope
- AA 22-41
- Isotype
- IgG
- Vial size
- 0.1 mL
- Storage
- After reconstitution, use immediately or refrigerate at 2 - 8°C up to 2 days. For long-term storage aliquot antibody and freeze at -15°C or lower. Avoid repeated freeze/thaw cycles.
Submitted references Chronic spinal cord injury causes upregulation of serotonin (5-HT)2A and 5-HT2C receptors in lumbosacral cord motoneurons.
Loss of motoneurons in the ventral compartment of the rat hypoglossal nucleus following early postnatal exposure to alcohol.
Grafting of fetal brainstem 5-HT neurons into the sublesional spinal cord of paraplegic rats restores coordinated hindlimb locomotion.
Circadian dependence of receptors that mediate wake-related excitatory drive to hypoglossal motoneurons.
Chronic mild stress modulates 5-HT1A and 5-HT2A receptor expression in the cerebellar cortex of NC/Nga atopic-like mice.
Sex differences in serotonin enhancement of capsaicin-evoked calcitonin gene-related peptide release from human dental pulp.
Characteristics of the actions by which 5-hydroxytryptamine affects electrical and mechanical activities in rabbit jugular vein graft.
Characteristics of the actions by which 5-HT affects electrical and mechanical activities in rabbit jugular vein.
Effect of chronic mild stress on serotonergic markers in the skin and brain of the NC/Nga atopic-like mouse strain.
Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats.
Contribution of 5-HT to locomotion - the paradox of Pet-1(-/-) mice.
The time course of serotonin 2A receptor expression after spinal transection of rats: an immunohistochemical study.
Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling.
Htr2a Gene and 5-HT(2A) Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice.
Robust upregulation of serotonin 2A receptors after chronic spinal transection of rats: an immunohistochemical study.
Enhancement of mesenteric artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2 diabetes.
Chronic treatment of hydroxytryptamine type 2a receptor antagonist sarpogrelate hydrochloride modulates the vasoreactivity of serotonin in experimental rabbit vein grafts.
The 5-HT2A receptor is mainly expressed in nociceptive sensory neurons in rat lumbar dorsal root ganglia.
Intracerebroventricular fluvoxamine administration inhibited pain behavior but increased Fos expression in affective pain pathways.
Stress impairs 5-HT2A receptor-mediated serotonergic facilitation of GABA release in juvenile rat basolateral amygdala.
Prenatal activation of 5-HT2A receptor induces expression of 5-HT1B receptor in phrenic motoneurons and alters the organization of their premotor network in newborn mice.
Serotonin 5-HT2A receptor involvement and Fos expression at the spinal level in vincristine-induced neuropathy in the rat.
Role of spinal serotonin 5-HT2A receptor in 2',3'-dideoxycytidine-induced neuropathic pain in the rat and the mouse.
Serotonin 5-HT2A and 5-HT5A receptors are expressed by different motoneuron populations in rat Onuf's nucleus.
The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence.
The 5-HT2A receptor is widely distributed in the rat spinal cord and mainly localized at the plasma membrane of postsynaptic neurons.
Brain 5-HT receptor system in the stressed infant rat: implications for vulnerability to substance abuse.
5-HT(2A) receptor-like protein is present in small neurons located in rat mesopontine cholinergic nuclei, but absent from cholinergic neurons.
Airway vasculature after mycoplasma infection: chronic leakiness and selective hypersensitivity to substance P.
Pontomedullary distribution of 5-HT2A receptor-like protein in the rat.
5-HT2a receptors in the rabbit retina: potential presynaptic modulators.
Cao N, Ni J, Wang X, Tu H, Gu B, Si J, Wu G, Andersson KE
BJU international 2018 Jan;121(1):145-154
BJU international 2018 Jan;121(1):145-154
Loss of motoneurons in the ventral compartment of the rat hypoglossal nucleus following early postnatal exposure to alcohol.
Stettner GM, Kubin L, Volgin DV
Journal of chemical neuroanatomy 2013 Sep;52:87-94
Journal of chemical neuroanatomy 2013 Sep;52:87-94
Grafting of fetal brainstem 5-HT neurons into the sublesional spinal cord of paraplegic rats restores coordinated hindlimb locomotion.
Sławińska U, Miazga K, Cabaj AM, Leszczyńska AN, Majczyński H, Nagy JI, Jordan LM
Experimental neurology 2013 Sep;247:572-81
Experimental neurology 2013 Sep;247:572-81
Circadian dependence of receptors that mediate wake-related excitatory drive to hypoglossal motoneurons.
Volgin DV, Stettner GM, Kubin L
Respiratory physiology & neurobiology 2013 Sep 15;188(3):301-7
Respiratory physiology & neurobiology 2013 Sep 15;188(3):301-7
Chronic mild stress modulates 5-HT1A and 5-HT2A receptor expression in the cerebellar cortex of NC/Nga atopic-like mice.
Rasul A, Johansson B, Lonne-Rahm SB, Nordlind K, Theodorsson E, El-Nour H
Archives of dermatological research 2013 Jul;305(5):407-13
Archives of dermatological research 2013 Jul;305(5):407-13
Sex differences in serotonin enhancement of capsaicin-evoked calcitonin gene-related peptide release from human dental pulp.
Loyd DR, Sun XX, Locke EE, Salas MM, Hargreaves KM
Pain 2012 Oct;153(10):2061-7
Pain 2012 Oct;153(10):2061-7
Characteristics of the actions by which 5-hydroxytryptamine affects electrical and mechanical activities in rabbit jugular vein graft.
Maekawa T, Komori K, Kajikuri J, Itoh T
British journal of pharmacology 2012 Jun;166(4):1419-32
British journal of pharmacology 2012 Jun;166(4):1419-32
Characteristics of the actions by which 5-HT affects electrical and mechanical activities in rabbit jugular vein.
Itoh T, Kajikuri J
British journal of pharmacology 2011 Oct;164(3):979-91
British journal of pharmacology 2011 Oct;164(3):979-91
Effect of chronic mild stress on serotonergic markers in the skin and brain of the NC/Nga atopic-like mouse strain.
Rasul A, El-Nour H, Blakely RD, Lonne-Rahm SB, Forsberg J, Johansson B, Theodorsson E, Nordlind K
Archives of dermatological research 2011 Nov;303(9):625-33
Archives of dermatological research 2011 Nov;303(9):625-33
Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats.
Dumitrascu R, Kulcke C, Königshoff M, Kouri F, Yang X, Morrell N, Ghofrani HA, Weissmann N, Reiter R, Seeger W, Grimminger F, Eickelberg O, Schermuly RT, Pullamsetti SS
The European respiratory journal 2011 May;37(5):1104-18
The European respiratory journal 2011 May;37(5):1104-18
Contribution of 5-HT to locomotion - the paradox of Pet-1(-/-) mice.
Pearlstein E, Bras H, Deneris ES, Vinay L
The European journal of neuroscience 2011 May;33(10):1812-22
The European journal of neuroscience 2011 May;33(10):1812-22
The time course of serotonin 2A receptor expression after spinal transection of rats: an immunohistochemical study.
Kong XY, Wienecke J, Chen M, Hultborn H, Zhang M
Neuroscience 2011 Mar 17;177:114-26
Neuroscience 2011 Mar 17;177:114-26
Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling.
Coulon P, Kanyshkova T, Broicher T, Munsch T, Wettschureck N, Seidenbecher T, Meuth SG, Offermanns S, Pape HC, Budde T
Frontiers in cellular neuroscience 2010;4:132
Frontiers in cellular neuroscience 2010;4:132
Htr2a Gene and 5-HT(2A) Receptor Expression in the Cerebral Cortex Studied Using Genetically Modified Mice.
Weber ET, Andrade R
Frontiers in neuroscience 2010;4
Frontiers in neuroscience 2010;4
Robust upregulation of serotonin 2A receptors after chronic spinal transection of rats: an immunohistochemical study.
Kong XY, Wienecke J, Hultborn H, Zhang M
Brain research 2010 Mar 12;1320:60-8
Brain research 2010 Mar 12;1320:60-8
Enhancement of mesenteric artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2 diabetes.
Matsumoto T, Kobayashi T, Ishida K, Taguchi K, Kamata K
British journal of pharmacology 2010 Jul;160(5):1092-104
British journal of pharmacology 2010 Jul;160(5):1092-104
Chronic treatment of hydroxytryptamine type 2a receptor antagonist sarpogrelate hydrochloride modulates the vasoreactivity of serotonin in experimental rabbit vein grafts.
Kodama A, Komori K, Kajikuri J, Itoh T
Journal of vascular surgery 2009 Sep;50(3):617-25
Journal of vascular surgery 2009 Sep;50(3):617-25
The 5-HT2A receptor is mainly expressed in nociceptive sensory neurons in rat lumbar dorsal root ganglia.
Van Steenwinckel J, Noghero A, Thibault K, Brisorgueil MJ, Fischer J, Conrath M
Neuroscience 2009 Jul 7;161(3):838-46
Neuroscience 2009 Jul 7;161(3):838-46
Intracerebroventricular fluvoxamine administration inhibited pain behavior but increased Fos expression in affective pain pathways.
Hayashi T, Miyata M, Nagata T, Izawa Y, Kawakami Y
Pharmacology, biochemistry, and behavior 2009 Jan;91(3):441-6
Pharmacology, biochemistry, and behavior 2009 Jan;91(3):441-6
Stress impairs 5-HT2A receptor-mediated serotonergic facilitation of GABA release in juvenile rat basolateral amygdala.
Jiang X, Xing G, Yang C, Verma A, Zhang L, Li H
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009 Jan;34(2):410-23
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009 Jan;34(2):410-23
Prenatal activation of 5-HT2A receptor induces expression of 5-HT1B receptor in phrenic motoneurons and alters the organization of their premotor network in newborn mice.
Bras H, Gaytán SP, Portalier P, Zanella S, Pásaro R, Coulon P, Hilaire G
The European journal of neuroscience 2008 Sep;28(6):1097-107
The European journal of neuroscience 2008 Sep;28(6):1097-107
Serotonin 5-HT2A receptor involvement and Fos expression at the spinal level in vincristine-induced neuropathy in the rat.
Thibault K, Van Steenwinckel J, Brisorgueil MJ, Fischer J, Hamon M, Calvino B, Conrath M
Pain 2008 Nov 30;140(2):305-22
Pain 2008 Nov 30;140(2):305-22
Role of spinal serotonin 5-HT2A receptor in 2',3'-dideoxycytidine-induced neuropathic pain in the rat and the mouse.
Van Steenwinckel J, Brisorgueil MJ, Fischer J, Vergé D, Gingrich JA, Bourgoin S, Hamon M, Bernard R, Conrath M
Pain 2008 Jul;137(1):66-80
Pain 2008 Jul;137(1):66-80
Serotonin 5-HT2A and 5-HT5A receptors are expressed by different motoneuron populations in rat Onuf's nucleus.
Xu C, Giuliano F, Sun XQ, Brisorgueil MJ, Leclerc P, Vergé D, Conrath M
The Journal of comparative neurology 2007 Jun 1;502(4):620-34
The Journal of comparative neurology 2007 Jun 1;502(4):620-34
The pre-nervous serotonergic system of developing sea urchin embryos and larvae: pharmacologic and immunocytochemical evidence.
Buznikov GA, Peterson RE, Nikitina LA, Bezuglov VV, Lauder JM
Neurochemical research 2005 Jun-Jul;30(6-7):825-37
Neurochemical research 2005 Jun-Jul;30(6-7):825-37
The 5-HT2A receptor is widely distributed in the rat spinal cord and mainly localized at the plasma membrane of postsynaptic neurons.
Doly S, Madeira A, Fischer J, Brisorgueil MJ, Daval G, Bernard R, Vergé D, Conrath M
The Journal of comparative neurology 2004 May 10;472(4):496-511
The Journal of comparative neurology 2004 May 10;472(4):496-511
Brain 5-HT receptor system in the stressed infant rat: implications for vulnerability to substance abuse.
Vázquez DM, Eskandari R, Zimmer CA, Levine S, López JF
Psychoneuroendocrinology 2002 Jan-Feb;27(1-2):245-72
Psychoneuroendocrinology 2002 Jan-Feb;27(1-2):245-72
5-HT(2A) receptor-like protein is present in small neurons located in rat mesopontine cholinergic nuclei, but absent from cholinergic neurons.
Fay R, Kubin L
Neuroscience letters 2001 Nov 13;314(1-2):77-81
Neuroscience letters 2001 Nov 13;314(1-2):77-81
Airway vasculature after mycoplasma infection: chronic leakiness and selective hypersensitivity to substance P.
Kwan ML, Gómez AD, Baluk P, Hashizume H, McDonald DM
American journal of physiology. Lung cellular and molecular physiology 2001 Feb;280(2):L286-97
American journal of physiology. Lung cellular and molecular physiology 2001 Feb;280(2):L286-97
Pontomedullary distribution of 5-HT2A receptor-like protein in the rat.
Fay R, Kubin L
The Journal of comparative neurology 2000 Mar 13;418(3):323-45
The Journal of comparative neurology 2000 Mar 13;418(3):323-45
5-HT2a receptors in the rabbit retina: potential presynaptic modulators.
Pootanakit K, Prior KJ, Hunter DD, Brunken WJ
Visual neuroscience 1999 Mar-Apr;16(2):221-30
Visual neuroscience 1999 Mar-Apr;16(2):221-30
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