BS7398

antibody from Bioworld Technology, Inc
Targeting: EDN3 ET3
Provider product page for BS7398
Western blot
Immunohistochemistry

Antibody data

Product number
BS7398 - Provider product page
Provider
Bioworld Technology, Inc
Product name
EDN3 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human EDN3.
Description
The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
EDN3 protein structure - BS7398 shown in red.