Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- AF1375 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-26/AK155 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects human IL-26 in direct ELISAs and Western blots. In these formats, less than 5% cross-reactivity with recombinant human IL-10 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q9NPH9
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes.
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation.
The role of the novel Th17 cytokine IL-26 in intestinal inflammation.
Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.
Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.
Ohnuma K, Hatano R, Aune TM, Otsuka H, Iwata S, Dang NH, Yamada T, Morimoto C
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3697-712
Journal of immunology (Baltimore, Md. : 1950) 2015 Apr 15;194(8):3697-712
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation.
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, Hoppe E, Barré B, Audran M, Bouvard B, Saint-André JP, Jeannin P
PLoS biology 2012;10(9):e1001395
PLoS biology 2012;10(9):e1001395
The role of the novel Th17 cytokine IL-26 in intestinal inflammation.
Dambacher J, Beigel F, Zitzmann K, De Toni EN, Göke B, Diepolder HM, Auernhammer CJ, Brand S
Gut 2009 Sep;58(9):1207-17
Gut 2009 Sep;58(9):1207-17
Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.
Sheikh F, Baurin VV, Lewis-Antes A, Shah NK, Smirnov SV, Anantha S, Dickensheets H, Dumoutier L, Renauld JC, Zdanov A, Donnelly RP, Kotenko SV
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2006-10
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2006-10
Cutting edge: IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2.
Sheikh F, Baurin VV, Lewis-Antes A, Shah NK, Smirnov SV, Anantha S, Dickensheets H, Dumoutier L, Renauld JC, Zdanov A, Donnelly RP, Kotenko SV
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2006-10
Journal of immunology (Baltimore, Md. : 1950) 2004 Feb 15;172(4):2006-10
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