CABT-BL8409

antibody from Creative Diagnostics

Targeting: TSC22D3 DIP, DSIPI, GILZ, hDIP, TSC-22R

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL8409

Provider

Creative Diagnostics

Product name

Anti-TSC22D3 Monoclonal antibody, clone DGNLH26

Antibody type

Monoclonal

Description

The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-Kappa-B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.

Reactivity

Human, Mouse

Host

Rat

Conjugate

Unconjugated

Isotype

IgG