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- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Western blot [1]
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- Product number
- ABIN1881388 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-G Protein-Coupled Receptor 77 (GPR77) (C-Term), (AA 297-325) antibody
- Antibody type
- Polyclonal
- Antigen
- This GPR77 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human GPR77.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term,AA 297-325
- Antibody clone number
- RB42221
- Vial size
- 400 μL
- Concentration
- 0.29 mg/mL
Submitted references The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction.
C5a- and ASP-mediated C5L2 activation, endocytosis and recycling are lost in S323I-C5L2 mutation.
Recombinant C3adesArg/acylation stimulating protein (ASP) is highly bioactive: a critical evaluation of C5L2 binding and 3T3-L1 adipocyte activation.
The human complement fragment receptor, C5L2, is a recycling decoy receptor.
The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding.
An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2.
Bamberg CE, Mackay CR, Lee H, Zahra D, Jackson J, Lim YS, Whitfeld PL, Craig S, Corsini E, Lu B, Gerard C, Gerard NP
The Journal of biological chemistry 2010 Mar 5;285(10):7633-44
The Journal of biological chemistry 2010 Mar 5;285(10):7633-44
C5a- and ASP-mediated C5L2 activation, endocytosis and recycling are lost in S323I-C5L2 mutation.
Cui W, Simaan M, Laporte S, Lodge R, Cianflone K
Molecular immunology 2009 Sep;46(15):3086-98
Molecular immunology 2009 Sep;46(15):3086-98
Recombinant C3adesArg/acylation stimulating protein (ASP) is highly bioactive: a critical evaluation of C5L2 binding and 3T3-L1 adipocyte activation.
Cui W, Lapointe M, Gauvreau D, Kalant D, Cianflone K
Molecular immunology 2009 Oct;46(16):3207-17
Molecular immunology 2009 Oct;46(16):3207-17
The human complement fragment receptor, C5L2, is a recycling decoy receptor.
Scola AM, Johswich KO, Morgan BP, Klos A, Monk PN
Molecular immunology 2009 Mar;46(6):1149-62
Molecular immunology 2009 Mar;46(6):1149-62
The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding.
Scola AM, Higginbottom A, Partridge LJ, Reid RC, Woodruff T, Taylor SM, Fairlie DP, Monk PN
The Journal of biological chemistry 2007 Feb 9;282(6):3664-71
The Journal of biological chemistry 2007 Feb 9;282(6):3664-71
An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2.
Gerard NP, Lu B, Liu P, Craig S, Fujiwara Y, Okinaga S, Gerard C
The Journal of biological chemistry 2005 Dec 2;280(48):39677-80
The Journal of biological chemistry 2005 Dec 2;280(48):39677-80
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- GPR77 Antibody (C-term) (ABIN1881388) western blot analysis in A549 cell line lysates (35 μg/lane). This demonstrates the GPR77 antibody detected the GPR77 protein (arrow).
