Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN153223 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-WNK Lysine Deficient Protein Kinase 4 (WNK4) (AA 200-300) antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- AA 200-300
- Vial size
- 0.1 mL
- Storage
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references High frequency and wide range of human kidney papillary crystalline plugs.
FGF23 promotes renal calcium reabsorption through the TRPV5 channel.
Immunolocalization of WNK4 in mouse kidney.
Pathophysiological roles of WNK kinases in the kidney.
WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction.
Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats.
WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia.
Human hypertension caused by mutations in WNK kinases.
Huguet L, Le Dudal M, Livrozet M, Bazin D, Frochot V, Perez J, Haymann JP, Brocheriou I, Daudon M, Letavernier E
Urolithiasis 2018 Aug;46(4):333-341
Urolithiasis 2018 Aug;46(4):333-341
FGF23 promotes renal calcium reabsorption through the TRPV5 channel.
Andrukhova O, Smorodchenko A, Egerbacher M, Streicher C, Zeitz U, Goetz R, Shalhoub V, Mohammadi M, Pohl EE, Lanske B, Erben RG
The EMBO journal 2014 Feb 3;33(3):229-46
The EMBO journal 2014 Feb 3;33(3):229-46
Immunolocalization of WNK4 in mouse kidney.
Ohno M, Uchida K, Ohashi T, Nitta K, Ohta A, Chiga M, Sasaki S, Uchida S
Histochemistry and cell biology 2011 Jul;136(1):25-35
Histochemistry and cell biology 2011 Jul;136(1):25-35
Pathophysiological roles of WNK kinases in the kidney.
Uchida S
Pflugers Archiv : European journal of physiology 2010 Sep;460(4):695-702
Pflugers Archiv : European journal of physiology 2010 Sep;460(4):695-702
WNK4 diverts the thiazide-sensitive NaCl cotransporter to the lysosome and stimulates AP-3 interaction.
Subramanya AR, Liu J, Ellison DH, Wade JB, Welling PA
The Journal of biological chemistry 2009 Jul 3;284(27):18471-80
The Journal of biological chemistry 2009 Jul 3;284(27):18471-80
Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats.
Song J, Hu X, Riazi S, Tiwari S, Wade JB, Ecelbarger CA
American journal of physiology. Renal physiology 2006 May;290(5):F1055-64
American journal of physiology. Renal physiology 2006 May;290(5):F1055-64
WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia.
Kahle KT, Gimenez I, Hassan H, Wilson FH, Wong RD, Forbush B, Aronson PS, Lifton RP
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 17;101(7):2064-9
Proceedings of the National Academy of Sciences of the United States of America 2004 Feb 17;101(7):2064-9
Human hypertension caused by mutations in WNK kinases.
Wilson FH, Disse-Nicodème S, Choate KA, Ishikawa K, Nelson-Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, Lifton RP
Science (New York, N.Y.) 2001 Aug 10;293(5532):1107-12
Science (New York, N.Y.) 2001 Aug 10;293(5532):1107-12
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB