BS9130

antibody from Bioworld Technology, Inc
Targeting: COL4A6
Provider product page for BS9130
Western blot
Immunohistochemistry

Antibody data

Product number
BS9130 - Provider product page
Provider
Bioworld Technology, Inc
Product name
COL4A6 (G1223) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 1190-1240 of Human COL4A6.
Description
Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. Collagens contain triple helix domains and frequently show lateral selfassociation in order to form complex connective tissues. Several collagens play a role in cell adhesion, which is important for maintaining normal tissue architecture and function. COL4A6 (collagen, type IV, Ï« 6) is a 1,691 amino acid secreted protein belonging to the type IV collagen family. Type IV collagen, a major component of the basement membrane (BM), is composed of six genetically distinct Ï«(IV) chains, Ï«1(IV) to Ï«6(IV). Defects in the gene encoding COL4A6 is believed is the cause of X-linked Alport syndrome (AS), which is characterized by macroscopic hematuria, cataracts and leiomyomatosis.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
COL4A6 protein structure - BS9130 shown in red.