APR01944G

antibody from Leading Biology

Targeting: GRM5 GPRC1E, mGlu5, MGLUR5, PPP1R86

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR01944G

Provider

Leading Biology

Product name

GRM5 / MGLUR5 Antibody (C-Terminus)

Antibody type

Polyclonal

Description

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.

Reactivity

Human, Mouse, Bovine, Canine, Horse, Simian

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.