Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- AF3904 - Provider product page
- Provider
- R&D Systems
- Product name
- Human MuSK Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human MuSK in direct ELISAs and Western blots. In direct ELISAs, less than 40% cross-reactivity with recombinant rat MuSK is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
O15146
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Preserving neuromuscular synapses in ALS by stimulating MuSK with a therapeutic agonist antibody.
Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L.
Cantor S, Zhang W, Delestrée N, Remédio L, Mentis GZ, Burden SJ
eLife 2018 Feb 20;7
eLife 2018 Feb 20;7
Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L.
Hallock PT, Xu CF, Park TJ, Neubert TA, Curran T, Burden SJ
Genes & development 2010 Nov 1;24(21):2451-61
Genes & development 2010 Nov 1;24(21):2451-61
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