BS7174

antibody from Bioworld Technology, Inc
Targeting: NPHS1 CNF, NPHN
Provider product page for BS7174
Western blot
Immunohistochemistry

Antibody data

Product number
BS7174 - Provider product page
Provider
Bioworld Technology, Inc
Product name
Nephrin polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human Nephrin.
Description
Nephrin is a member of the immunoglobulin family of cell adhesion molecules that localizes to opposing sites of the secondary foot processes formed by podocytes, a specialized epithelial cell that ensures size- and charge-selective ultrafiltration. The human nephrin gene maps to chromosome 19q13.1 and encodes a 1,241 amino acid protein that contains a transmembrane domain, 8 Ig-like modules, and 1 fibronectin III-like module. Nephrin is expressed in embryonic and adult kidneys and localizes to glomerular podocytes and the glomerular slit diaphragm. Nephrin stimulates mitogen-activated protein kinases and is enhanced by podocin, which binds to the cytoplasmic tail of nephrin.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NPHS1 protein structure - BS7174 shown in red.