BS8202

antibody from Bioworld Technology, Inc
Targeting: CLEC3B TN, TNA
Provider product page for BS8202
Western blot
Immunohistochemistry

Antibody data

Product number
BS8202 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CLEC3B polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CLEC3B.
Description
Tetranectin is a homotrimeric glycoprotein present in plasma and various tissue locations that binds to calcium, heparin, and plasminogen kringle 4. Tetranectin may play a prominent role in tissue remodeling as well as in the regulation of proteolytic processes via its binding and indirect activation of plasminogen. Tetranectin is found in the extracellular matrix (ECM) of certain carcinomas, but is not present in the ECM of normal tissues. Extracellular proteolysis is an important factor in the ability of malignant cells to penetrate normal tissues and metastasize. Decreased plasma tetranectin or increased tetranectin in stroma of cancers correlates with cancer progression and a grim prognosis. Tetranectin may also influence cancer growth by altering activities of plasminogen or the plasminogen fragment, angiostatin which inhibits tumor cell proliferation.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CLEC3B protein structure - BS8202 shown in red.