130-00013-100

antibody from RayBiotech, Inc.

Targeting: AGRP Agrt, ART, ASIP2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

130-00013-100

Provider

RayBiotech, Inc.

Product name

Rabbit Anti-Human AGRP

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Agouti-related protein also called Agouti-related peptide (AgRP) is a neuropeptide produced in the brainby the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalamus. AgRP is co-expressed with Neuropeptide Y and works by increasing appetite and decreasing metabolism and energy expenditure. It is one of the most potent and long-lasting of appetite stimulators. In humans, the agouti-related peptide is encoded by the AGRP gene. It has been found that AgRP stimulates the hypothalamic-pituitary-adrenocortical axis to release ACTH, cortisol and prolactin. It also enhances the ACTH response to IL-1-beta, suggesting it may play a role in the modulation of neuroendocrine response to inflammation. This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified from rabbit serum by Protein G affinity chromatography.

Reactivity

Human

Host

Rabbit

Antigen sequence

This antibody was produced from a r
abbit immunized with this peptide c
onjugated with KLH. The IgG fractio
n was purified from rabbit serum by
Protein G affinity chromatography.


Isotype

IgG

Vial size

100 µg

Handling

Product is supplied as a powder obtained from lyophilization of purified antibody in PBS without preservatives. Reconstitute the antibody with sterile 1 x PBS to a final concentration of 1 mg/ml.