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Protein structure
XCR1
X-C motif chemokine receptor 1CCXCR1, GPR5
The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2020]
Top validated antibodies |
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| Novus Biologicals |  NBP1-02343 |
1 references | Polyclonal |
WB
ICC
IHC
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| NSJ Bioreagents | RQ7347 |
Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN2845364 |
4 references | Polyclonal |
WB
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| R&D Systems | AF857 |
Polyclonal |
WB
ICC
FC
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| Affinity Biosciences | DF9046 |
Polyclonal |
WB
EL
IHC
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