FNab08119

antibody from FineTest Biotech
Targeting: SOST DAND6, VBCH
Provider product page for FNab08119
Western blot
ELISA
Immunohistochemistry

Antibody data

Product number
FNab08119 - Provider product page
Provider
FineTest Biotech
Product name
SOST antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
sclerosteosis
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
SOST protein structure - FNab08119 shown in red.